Diabetes Clinical Trials

Showing 241-260 of 3,811 trials

Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers

NCT02724566

Preclinical studies have demonstrated in mouse models that (PYR1)-apelin-13 exerts a glucose-regulating action in vivo. The (PYR1)-apelin-13 effect on insulin sensitivity in healthy overweighed volunteers has been previously assessed in a phase I clinical trial (APELINS study; NCT02033473). The APELINS-2 clinical trial aims to expand the initial proof of concept to the population targeted by future innovative insulin-sensitizing therapies: patients living with type 2 diabetes.

Diabetes

University Hospital, Toulouse9 participantsStarted May 2016

Toulouse, Midi-Pyrénées, France

RECRUITINGPHASE2

Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes

NCT05180591

The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediatric Type 1 diabetes.

Diabetes Mellitus, Type 1Diabetes type1Autoimmune Diabetes

Massachusetts General Hospital150 participantsStarted Mar 2022

Charlestown, Massachusetts, United States

ACTIVE_NOT_RECRUITINGNA

Resistance Training for the Improvement of Glycemic Control in Prediabetes

NCT06697756

The purpose of this research is to study the effects of resistance exercise training with different degrees of effort on your glucose responses (what we call glycemic control) and psychological responses.

Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)

University of New Mexico48 participantsStarted Nov 2024

Albuquerque, New Mexico, United States

Effect of Apelin on Insulin Sensitivity in Type 2 Diabetic Volunteers

Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes

Resistance Training for the Improvement of Glycemic Control in Prediabetes

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