Crohn's Disease Clinical Trials in Los Angeles

Showing 1-20 of 65 trials

MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)

NCT04578392

Study description - Patients will be randomized according to post-operative recurrence risk to either a high ligation of ileocolic artery or mesenteric sparing ileocolic resection for terminal ileal Crohn's disease. The primary endpoint 6-month endoscopic recurrence. Endpoints - Primary endpoint; 6 months Secondary endpoints at 1 and 5 years post ileocecal resection Study population - Adult Crohn's disease patients with medically refractory terminal ileal Crohn's disease undergoing a primary ileocecal resection. Study sites - Multicenter international study Description of study intervention - Randomized control trial of two operative techniques Operative approach of a high ligation of ileocolic artery as compared to mesenteric sparing for a primary ileocolic resection Participate duration - 5 years

Crohn Disease

The Cleveland Clinic13 participantsStarted Jul 2020

Los Angeles, California, United States • Stanford, California, United States • Weston, Florida, United States +4 more locations

COMPLETEDPhase 2< 1 mile

Long-term Safety With Vedolizumab Intravenous (IV) in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD)

NCT03196427

The purpose of this study is to determine the safety profile of long-term vedolizumab IV treatment in pediatric participants with UC or CD.

Ulcerative ColitisCrohn's Disease

Takeda59 participantsStarted Jul 2018

Los Angeles, California, United States • Orange, California, United States • San Francisco, California, United States +20 more locations

MeSenteric SpAring Versus High Ligation Ileocolic Resection for the Prevention of REcurrent Crohn's DiseaSe (SPARES)

Long-term Safety With Vedolizumab Intravenous (IV) in Pediatric Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD)

Crohn's Disease Trials in Other Cities

An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

Pilot Study of Posaconazole in Crohn's Disease

A Study of Guselkumab Subcutaneous Therapy in Participants With Moderately to Severely Active Crohn's Disease

VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease

Study of Dietary Composition in Crohn's Disease

A Study to Evaluate MORF-057 in Adults With Moderately to Severely Active UC

An Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn's Disease

A Maintenance and Long-Term Extension Study of the Efficacy and Safety of Upadacitinib (ABT-494) in Participants With Crohn's Disease Who Completed the Studies M14-431 or M14-433

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis

A Study to Test Whether BI 706321 Combined With Ustekinumab Helps People With Crohn's Disease

A Study of Vedolizumab in Children and Teenagers With Ulcerative Colitis or Crohn's Disease

A Study of CDPATH™ to Help Manage and Treat Crohn's Disease

Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease

A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease

A Study Evaluating the Efficacy and Safety of Oral Etrasimod in the Treatment of Adult Participants With Moderately to Severely Active Crohn's Disease

Treatment of Moderate to Severe Refractory Crohn's Disease

Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)

Other Conditions in Los Angeles