COVID-19 Clinical Trials

Showing 1181-1200 of 1,603 trials

Chronic Multimorbidity Patterns in Relation to COVID-19 Severe Infection

NCT04981249

The aim of the study was to analyze the patterns of chronic multimorbidity of a cohort of Covid-19 patients, and to assess the relation between the patterns and the development of severe infection or mortality.

Covid-19Chronic Disease

Corporacion Parc Tauli14,286 participantsStarted Jan 2021

Sabadell, Spain

UNKNOWN

Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome

NCT04408326

This study aims to find out whether the use of angiotensin II, which is a drug to raise blood pressure has been approved by European Medical Agency in August 2019, as an add-on medication to increase blood pressure in patients with COVID-19, acute severe lung injury, inflammation and severe shock, compared with standard medication. In addition, the investigators will collect the data of Anakinra, another drug which is frequently used in this condition to reduce inflammation. The investigators will collect clinical data and outcomes from critical care patients. The investigators will analyse for whom these drugs are most beneficial and explore whether there are any patients who don't benefit or have side effects.

COVIDAcute Respiratory Distress Syndrome

Guy's and St Thomas' NHS Foundation Trust50 participantsStarted Jun 2020

London, United Kingdom

UNKNOWNPhase 3

Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19

NCT04979221

This randomized controled open label clinical trial conducted in patients with hypoxemic respiratory failure admitted to the ICU and requiring ventilatory support (invasive or non-invasive) is to evaluate whether treatment with cyproheptadine, a serotonin receptor antagonist, compared to usual care, increases the number of ventilator-free days.

COVID-19 Pneumonia

Hospital de Clinicas de Porto Alegre274 participantsStarted Jul 2021

Porto Alegre, Rio Grande do Sul, Brazil

Chronic Multimorbidity Patterns in Relation to COVID-19 Severe Infection

Efficacy and Safety of Angiotensin II Use in Coronavirus Disease(COVID)-19 Patients With Acute Respiratory Distress Syndrome

Effect of Cyproheptadine on Ventilatory Support-free Days in Critically Ill Patients With COVID-19

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Evaluation of the Effect and Side Effect Profile of Covid-19 Vaccine in Cancer Patients

Clinical, Functional, Immunological and Genetic Factors on the Severity of the Course of Coronavirus Infection

Assessment of Diurnal Salivary Cortisol Production in COVID-19

Use of a Respiratory Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Patients With Severe Confirmed COVID-19 Pneumonia

POC SARS-CoV-2 Diagnostic PCR Device Comparison to FDA Approved Reference PCR Test

Efficacy of Nebulized Lidocaine, Salbutamol, and Beclomethasone Plus Salbutamol in the Covid-19 Patients With ARDS on Non-invasive Ventilation; Randomized Control Trial

Natural Language Processing (NLP) Analysis of Free Text Notes to Investigate Coronavirus (COVID-19)

COVID-19 Infections and Mortality in Long-term Care Facilities During the First Wave

HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)

The Effect of Behaviour Change Interventions on Use of Public Handwashing Stations in Bangladesh

Effects of Respiratory Muscle Training in Patients With Post COVID-19

Risk Stratification of COVID-19 Patients Discharged From the Emergency Department

Prone Positioning and Regional Ventilation in Mechanically Ventilated COVID-19 Patients

Clinical Impact of COVID-19 by P.1 SARS-CoV-2 Lineage

Benefits of Using a Transparent Visor to Replace the Face Mask in Speech Therapy Rehabilitation of Oral-Linguo-Facial Praxies in the Context of COVID-19: a Series of Cases

Changes in Physical Activity Status: Comparison of Older Adults With Versus Without a History of Covid-19 Infection

A Study to Assess the Safety and Immunogenicity of the Coronavac Vaccine Against COVID-19