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Clinical Trials Colorectal CancerTennessee

Colorectal Cancer Clinical Trials in Tennessee

Find 454 clinical trials for colorectal cancer near Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 81-100 of 454 trials

RecruitingA Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02)This study is designed to assess the efficacy and safety of ifinatamab deruxtecan (I-DXD) in the following tumor types: endometrial cancer (EC); head and neck squamous cell…NCT06330064·Los Angeles, California and 119 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

TerminatedGenetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE TrialThis trial screens patients with colon or rectal cancer that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable) for genetic…NCT03765736·Scottsdale, Arizona and 17 others

RecruitingSolid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingObjective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect…NCT04981119·Gilbert, Arizona and 15 others

CompletedCPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced CancersThis is a Phase 1/1b open-label, dose escalation and dose expansion study of CPI-006, a humanized monoclonal antibody (mAb) targeting the CD73 cell-surface ectonucleotidase in…NCT03454451·Tucson, Arizona and 26 others

CompletedPhase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid TumorsThis is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in…NCT04344795·Aurora, Colorado and 10 others

CompletedCetuximab & Celecoxib for Metastatic Colorectal Cancer or Colorectal Cancer That Cannot Be Removed by SurgeryRATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00466505·Nashville, Tennessee

CompletedNovel PET/CT Imaging Biomarkers of CB-839 in Combination With Panitumumab and Irinotecan in Patients With Metastatic and Refractory RAS Wildtype Colorectal CancerThis phase I/II trial studies the best dose and side effects of glutaminase inhibitor CB-839 and how well it works with panitumumab and irinotecan hydrochloride (phase I only) in…NCT03263429·Nashville, Tennessee

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

RecruitingA Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid MalignanciesThe goal of this study is to learn if KQB368 works to treat advanced solid malignancies in adults. The study will also learn about the safety of KQB368.NCT07542704·Los Angeles, California and 13 others

UnknownCAR-macrophages for the Treatment of HER2 Overexpressing Solid TumorsPhase 1, first-in-human, open label study of CAR macrophages in HER2 overexpressing solid tumors.NCT04660929·Duarte, California and 6 others

CompletedCelecoxib, Fluorouracil, and Radiation Therapy in Treating Patients With Stage II or Stage III Rectal Cancer That Can Be Removed By SurgeryRATIONALE: Celecoxib may stop the growth of tumor cells by blocking blood flow to the tumor and by blocking some of the enzymes needed for cell growth.NCT00336960·Nashville, Tennessee and 1 other

CompletedStudy of Enzastaurin With 5-Fluorouracil/Leucovorin (5-FU/LV) Plus Bevacizumab as Maintenance Regimen Following First Line Therapy for Metastatic Colon CancerThis study will evaluate the addition of enzastaurin to 5-FU (5-fluorouracil)/LV (leucovorin) plus bevacizumab in the maintenance of best response obtained with 6 cycles of…NCT00612586·Memphis, Tennessee and 25 others

CompletedEverolimus and OSI-906 for Patients With Refractory Metastatic Colorectal CancerThe purpose of this study is to determine the maximum tolerated dose (MTD) of the combination of OSI-906 and everolimus for the treatment of patients with refractory metastatic…NCT01154335·Fort Myers, Florida and 1 other

RecruitingClinical Trial of an Anti-cancer Drug, CA-4948 (Emavusertib), in Combination With Chemotherapy Treatment (FOLFOX Plus Bevacizumab) in Metastatic Colorectal CancerThis phase I trial studies the side effects and best dose of CA-4948 when given together with fluorouracil, leucovorin, oxaliplatin (FOLFOX) plus bevacizumab in treating patients…NCT06696768·Gainesville, Florida and 12 others

RecruitingA Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid TumorsSolid tumours are abnormal lumps of tissue that can occur in different parts of the body.NCT07213609·Aurora, Colorado and 26 others

CompletedS1613, Trastuzumab and Pertuzumab or Cetuximab and Irinotecan Hydrochloride in Treating Patients With Locally Advanced or Metastatic HER2/Neu Amplified Colorectal Cancer That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well trastuzumab and pertuzumab work compared to cetuximab and irinotecan hydrochloride in treating patients with HER2/neu amplified…NCT03365882·Anchorage, Alaska and 797 others

CompletedA First-in-Human, Phase 1 Study of JAB-3312 in Adult Patients With Advanced Solid TumorsThis is a Phase 1, first-in-human, open-label dose-escalation study to determine the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D) and assess the DLT of…NCT04045496·Denver, Colorado and 3 others

CompletedAdapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor HealthThis research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors…NCT04000880·Birmingham, Alabama and 1 other

CompletedGlycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.NCT05259696·La Jolla, California and 12 others

TerminatedME-344 and Bevacizumab in Previously Treated Metastatic Colorectal CancerThis is a Phase 1b open-label, multiple dose/schedule sequential study to determine the safety and efficacy of the oxidative phosphorylation (OxPhos) pathway inhibitor ME-344 in…NCT05824559·Los Angeles, California and 6 others

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Other Conditions in Tennessee

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma