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Clareo Health | Colorectal Cancer Clinical Trials in Tennessee | 449 Studies

Clinical Trials Colorectal CancerTennessee

Colorectal Cancer Clinical Trials in Tennessee

Find 449 clinical trials for colorectal cancer near Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 61-80 of 449 trials

RecruitingA Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)This is an open-label multicenter, single-arm Phase II study of Fruquintinib in combination with FOLFIRI (leucovorin calcium (folinic acid), fluorouracil, and irinotecan) in…NCT07011576·Denver, Colorado and 13 others CompletedA Study to Evaluate the Safety, Tolerability, and Activity of TAK-931 in Participants With Metastatic Pancreatic Cancer, Metastatic Colorectal Cancer, and Other Advanced Solid TumorsThe purpose of this study is to confirm the safety and tolerability of TAK-931 in a cohort of Western participants with metastatic solid tumors and to evaluate the anti-tumor…NCT03261947·Denver, Colorado and 9 others

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Data from ClinicalTrials.govTerms

CompletedPhase 2 Study of DKN-01 in Colorectal CancerThis is a Phase 2 randomized, open-label, two-part, multicenter study with a safety run-in to evaluate efficacy and safety of DKN-01 plus FOLFIRI/FOLFOX and bevacizumab versus…NCT05480306·Tucson, Arizona and 39 others

CompletedA Study of Efficacy and Safety of Fruquintinib (HMPL-013) in Participants With Metastatic Colorectal CancerThis is a global, randomized, double-blind, placebo-controlled, multicenter phase 3 clinical trial to compare the efficacy and safety of fruquintinib plus best supportive care…NCT04322539·Phoenix, Arizona and 152 others

RecruitingA Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell TherapyThe goal of this clinical trial is to evaluate CHM-2101, an autologous CDH17 CAR T-cell therapy for the treatment of advanced gastrointestinal (GI) cancers that are relapsed or…NCT06055439·Atlanta, Georgia and 3 others

CompletedA Study of Coformulated Favezelimab/Pembrolizumab (MK-4280A) Versus Standard of Care in Subjects With Previously Treated Metastatic PD-L1 Positive Colorectal Cancer (MK-4280A-007)The purpose of this study is to assess the safety and efficacy of coformulated favezelimab/pembrolizumab (MK-4280A) in participants with metastatic colorectal cancer.NCT05064059·Washington D.C., District of Columbia and 151 others

CompletedStudy of Oxaliplatin/5-FU/Leucovorin Plus Vatalanib Versus Oxaliplatin/5-FU/Leucovorin in Patients With Previously Treated Metastatic Colorectal CancerThe purpose of this study is to compare treatment with oxaliplatin/5-FU/leucovorin plus vatalanib versus oxaliplatin/5-FU/leucovorin plus placebo in patients with colorectal…NCT00056446·Huntsville, Alabama and 250 others

CompletedStudy of Vitamin D in Untreated Metastatic Colorectal CancerThis is a prospective, randomized, double-blind phase II trial to evaluate the efficacy and safety of two doses of vitamin D supplementation in combination with standard…NCT01516216·Boise, Idaho and 17 others

CompletedIrinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012389·Huntsville, Alabama and 153 others

TerminatedEvaluation of Revumenib in Participants With Colorectal Cancer and Other Solid TumorsThis study will evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of revumenib in participants with colorectal cancer (CRC) or other solid tumors…NCT05731947·Scottsdale, Arizona and 5 others

CompletedA Trial of PledOx + FOLFOX6 Compared to Placebo + FOLFOX6 in Patients With Metastatic Colorectal CancerThe present trial is designed to determine whether pre-treatment with PledOx lowers the frequency and severity of side effects from FOLFOX6 administration in patients with…NCT01619423·La Jolla, California and 32 others

TerminatedLinifanib in Treating Patients With Advanced, Refractory Colorectal CancerThis phase II trial studies how well Linifanib works in treating patients with advanced, refractory colorectal cancer expressing k-Ras mutations.NCT01365910·Franklin, Tennessee and 1 other

CompletedCetuximab and/or Bevacizumab Combined With Combination Chemotherapy in Treating Patients With Metastatic Colorectal CancerPURPOSE: This randomized phase III trial is studying cetuximab and/or bevacizumab when given together with combination chemotherapy to compare how well they work in treating…NCT00265850·Mobile, Alabama and 682 others

TerminatedME-344 and Bevacizumab in Previously Treated Metastatic Colorectal CancerThis is a Phase 1b open-label, multiple dose/schedule sequential study to determine the safety and efficacy of the oxidative phosphorylation (OxPhos) pathway inhibitor ME-344 in…NCT05824559·Los Angeles, California and 6 others

CompletedGW572016, An Oral Drug For Colorectal Cancer Patients Having Prior Therapy With 5-FU Plus CPT-11 And/Or OxaliplatinThe purpose of this study is to determine the efficacy of an oral investigational drug in patients with refractory metastatic colorectal cancer after receiving prior therapy with…NCT00044343·Los Angeles, California and 56 others

Active not recruitingImproving Care After Inherited Cancer TestingThe IMPACT Study seeks to refine and evaluate the effectiveness of interventions on improving guideline-adherent cancer risk management (CRM) and family communication (FC) of…NCT04763915·Nashville, Tennessee

CompletedAssessing Effectiveness and Implementation of an EHR Tool to Assess Heart Health Among SurvivorsThe objective of this hybrid effectiveness-implementation study is to examine the effects of an EHR-based cardiovascular health assessment tool (AH-HA) among breast, prostate…NCT03935282·Fort Smith, Arkansas and 11 others

TerminatedStudy Comparing Optimized 5-FU Dosing and Standard Dosing in Metastatic Colorectal Cancer Patients Treated With mFOLFOX6The purpose of this study is to compare OnDose® based pharmacokinetic administration of 5-FU versus standard Body Surface Area (BSA) based administration of 5-FU in patients with…NCT01468623·Birmingham, Alabama and 57 others

TerminatedA Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid TumorsThis study aims to evaluate the safety, and early signals of anti-tumor activity of PF-07820435 when administered alone (Part 1A) or in combination with sasanlimab (Part 1B; Part…NCT06285097·Sarasota, Florida and 9 others

TerminatedGenetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE TrialThis trial screens patients with colon or rectal cancer that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable) for genetic…NCT03765736·Scottsdale, Arizona and 17 others

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Other Conditions in Tennessee

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma