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Clareo Health | Colorectal Cancer Clinical Trials in Pittsburgh | 201 Studies

Clinical Trials Colorectal CancerPittsburgh

Colorectal Cancer Clinical Trials in Pittsburgh

Find 201 clinical trials for colorectal cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 201 trials

CompletedA Phase 2 Study of Pembrolizumab (MK-3475) in Combination With Azacitidine in Subjects With Chemo-refractory Metastatic Colorectal CancerThis is an open label, single-arm, Phase 2 trial to evaluate the anti-tumor activity, safety, and tolerability of Pembrolizumab in combination with azacitidine in subjects with…NCT02260440·Pittsburgh, Pennsylvania CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

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Data from ClinicalTrials.govTerms

TerminatedStudy of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intratumorally in…NCT04144140·New Haven, Connecticut and 12 others

CompletedLaparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon CancerRATIONALE: Less invasive types of surgery may help reduce the number of side effects and improve recovery.NCT00002575·Huntsville, Alabama and 157 others

CompletedMonoclonal Antibody Plus Chemotherapy in Treating Patients With Advanced Colorectal Cancer That Overexpresses HER2Phase II trial to study the effectiveness of the monoclonal antibody trastuzumab and chemotherapy with irinotecan in treating patients who have stage IV colorectal cancer that…NCT00003995·The Bronx, New York and 4 others

CompletedMotexafin Gadolinium and Doxorubicin in Treating Patients With Advanced CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00036790·Pittsburgh, Pennsylvania and 1 other

Active not recruitingStudy of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid TumorsThis is a multicenter Phase 1b, open-label study to assess safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of cabozantinib taken in combination with…NCT03170960·Gilbert, Arizona and 123 others

UnknownPanitumumab, Regorafenib, or TAS-102, in Treating Patients With Metastatic and/or Unresectable RAS Wild-Type Colorectal CancerThis phase II trial studies how well retreatment with panitumumab works compared to standard of care regorafenib or trifluridine and tipiracil hydrochloride (TAS-102) in treating…NCT03992456·Scottsdale, Arizona and 17 others

CompletedNSABP Patient Registry and Biospecimen Profiling RepositoryThis is a study to collect and analyze tissue specimens from metastatic colorectal cancer (mCRC) patients for the development of a molecularly profiled tissue repository for the…NCT01793805·Duarte, California and 45 others

CompletedA Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic CancerThe purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other…NCT02857270·Washington D.C., District of Columbia and 12 others

CompletedPhase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid TumorsThis is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in…NCT04344795·Aurora, Colorado and 10 others

TerminatedA Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.This was a clinical study with an orally administered drug, BDTX-189 in participants with advanced solid tumors that had select mutations or alterations in human epidermal growth…NCT04209465·Scottsdale, Arizona and 37 others

CompletedPhase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01876 when given in combination with immune therapies in subjects with advanced or…NCT03126110·Los Angeles, California and 37 others

UnknownStudy of Pembrolizumab With Pemetrexed and Oxaliplatin in Chemo-Refractory Metastatic Colorectal Cancer PatientsThis is a Phase Ib study to evaluate the safety and preliminary anti-tumor activity of pembrolizumab in combination with pemetrexed with or without oxaliplatin in patients with…NCT03626922·Gainesville, Florida and 14 others

RecruitingA Phase II Platform Study to Evaluate Treatment With Cemiplimab Monotherapy or Cemiplimab Plus Fianlimab or Other Novel Combinations in Patients With Colorectal Cancer With Minimal Residual Disease Following Definitive Surgery and Chemotherapy (EMPIRE)The NSABP FC-13 study is being done to determine if using immunotherapies alone or in combination with other drugs will delay or prevent colorectal cancer from coming back in…NCT07058012·Gainesville, Florida and 12 others

Active not recruitingA Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid TumorsThe main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally advanced or metastatic solid…NCT06607185·Birmingham, Alabama and 44 others

CompletedGefitinib in Treating Patients With Recurrent Metastatic Colorectal CancerRATIONALE: Biological therapies such as gefitinib may interfere with the growth of the tumor cells and slow the growth of recurrent metastatic colorectal cancer.NCT00025350·Chicago, Illinois and 15 others

RecruitingCabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal MalignanciesThe investigators propose to evaluate the safety of drug combinations in patients with advanced gastroesophageal cancer and other gastrointestinal (GI) malignancies.NCT03539822·Westwood, Kansas and 1 other

CompletedQuality Improvement of Patient-Provider Communication For Colorectal Cancer ScreeningThe immediate objective of this proposal is to assess the effectiveness of a multi-faceted intervention to improve patient-provider communication about colorectal cancer screening…NCT00324753·Chicago, Illinois and 2 others

CompletedAlpha-type-1 Dendritic Cell-based Vaccines in Patients With Metastatic Colorectal CancerThe purpose of this study is to evaluate the administration, safety and immunologic effectiveness of an experimental vaccine for colorectal cancer patients.NCT00558051·Pittsburgh, Pennsylvania

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