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Clareo Health | Colorectal Cancer Clinical Trials in Pittsburgh | 203 Studies

Clinical Trials Colorectal CancerPittsburgh

Colorectal Cancer Clinical Trials in Pittsburgh

Find 203 clinical trials for colorectal cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 61-80 of 203 trials

Active not recruitingA Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022.NCT02817633·Goodyear, Arizona and 88 others

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Data from ClinicalTrials.govTerms

CompletedSafety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651/KEYNOTE-651)The purpose of this study is to determine safety and tolerability and to establish a preliminary recommended Phase 2 dose (RP2D) for the following combinations: pembrolizumab plus…NCT03374254·Duarte, California and 13 others

CompletedPhotodynamic Therapy With Talaporfin Sodium (LS11) in Treating Patients With Refractory Colorectal Liver MetastasesThe purpose of this study is to determine whether the Litx platform is safe and effective in the treatment of liver metastasis arising from colorectal cancer.NCT00068068·Denver, Colorado and 5 others

Active not recruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C MutationThis is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or…NCT04449874·Duarte, California and 62 others

CompletedIrinotecan and Cetuximab for Colorectal Cancer as Second Line TherapyResearch Hypothesis: Subjects in the study population who are treated with cetuximab in combination with irinotecan will have higher response rates than subjects treated with…NCT00336856·Pittsburgh, Pennsylvania

CompletedGlycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.NCT05259696·La Jolla, California and 12 others

CompletedQuality Improvement of Patient-Provider Communication For Colorectal Cancer ScreeningThe immediate objective of this proposal is to assess the effectiveness of a multi-faceted intervention to improve patient-provider communication about colorectal cancer screening…NCT00324753·Chicago, Illinois and 2 others

CompletedA Study of Xeloda (Capecitabine) Plus Oxaliplatin in Patients With Colon CancerThis 2 arm study will compare the efficacy and safety of intermittent oral Xeloda plus Eloxatin (oxaliplatin) with that of fluorouracil/leucovorin in patients who have had surgery…NCT00069121·Mobile, Alabama and 231 others

Active not recruitingStudy of JANX008 in Subjects With Advanced or Metastatic Solid Tumor MalignanciesThis study is a first-in-human (FIH), Phase 1/1b, open-label, multicenter dose escalation and dose expansion study to assess the safety, tolerability, pharmacokinetics (PK)…NCT05783622·Duarte, California and 17 others

TerminatedStudy of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intratumorally in…NCT04144140·New Haven, Connecticut and 12 others

RecruitingA Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal CancerThe purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of…NCT07284849·Mobile, Alabama and 296 others

Active not recruitingDurvalumab and Tremelimumab With or Without High or Low-Dose Radiation Therapy in Treating Patients With Metastatic Colorectal or Non-small Cell Lung CancerThis randomized phase II trial studies the side effects of durvalumab and tremelimumab and to see how well they work with or without high or low-dose radiation therapy in treating…NCT02888743·Phoenix, Arizona and 41 others

CompletedIrinotecan With or Without Oxaliplatin in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012389·Huntsville, Alabama and 153 others

WithdrawnSafety and Efficacy Study of Neratinib and Cetuximab to Treat Patients With Quadruple Wild-Type Metastatic Colorectal CancerThe FC-7 study is designed as an open label, single arm, Phase I/II dose-escalation study evaluating the combination of neratinib and cetuximab in patients with metastatic…NCT01960023·Gainesville, Florida and 11 others

CompletedStudy of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer…NCT00063141·Tucson, Arizona and 187 others

CompletedA Phase II Multicenter, Randomized, Placebo Controlled, Double Blinded Clinical Study of KD018 as a Modulator of Irinotecan Chemotherapy in Patients With Metastatic Colorectal CancerThe proposed plan will investigate the mechanism and efficacy of Chinese herbal medicine as an adjunct to chemotherapy in treatment of patients with metastatic colorectal cancer.NCT00730158·New Haven, Connecticut and 1 other

Active not recruitingMOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid TumorsThe main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in…NCT06586515·Duarte, California and 51 others

CompletedA Study to Evaluate Immunotherapy Combinations in Participants With Gastrointestinal MalignanciesThis is a Phase 1/1b, open-label, dose-escalation, and dose-expansion study to evaluate the safety, tolerability, pharmacokinetic (PK), pharmacodynamic (PD), and clinical activity…NCT03720678·Tucson, Arizona and 23 others

RecruitingSafety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing TumorsA Phase 1 Open-Label, First-in-human, Dose Escalation and Expansion Study to Determine the Safety, Tolerability, Dosimetry, Pharmacokinetics, and Preliminary Efficacy of…NCT05283330·Chicago, Illinois and 7 others

CompletedImproving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVRImproving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR The goals of this study are to improve adherence to oral chemotherapeutic medications and…NCT02043184·New Haven, Connecticut and 7 others

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