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Clareo Health | Colorectal Cancer Clinical Trials in Philadelphia | 279 Studies

Clinical Trials Colorectal CancerPhiladelphia

Colorectal Cancer Clinical Trials in Philadelphia

Find 279 clinical trials for colorectal cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 121-140 of 279 trials

CompletedAn Investigational Immunotherapy Study of Nivolumab With Standard of Care Therapy vs Standard of Care Therapy for First-Line Treatment of Colorectal Cancer That Has SpreadThis purpose of this study is to evaluate nivolumab (BMS-936558) in combination with standard of care (SOC) chemotherapy with bevacizumab for the treatment of first-line…NCT03414983·Birmingham, Alabama and 48 others

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Data from ClinicalTrials.govTerms

TerminatedRegorafenib Plus 5-Fluorouracil/Leucovorin Beyond Progression in mCRCThis is a single arm open label pilot phase II trial of Regorafenib PO plus 5-FU/LV infusion in 15 mCRC patients who progressed on prior Regorafenib monotherapy as well as 5-FU…NCT03099486·Philadelphia, Pennsylvania

Active not recruitingFirst in Human Study of AZD9592 in Solid TumorsThis is a first-in-human (FIH) Phase I, multi-center, open-label, study of AZD9592, in patients with advanced solid tumors.NCT05647122·Duarte, California and 45 others

CompletedQUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal CarcinomaThis is a phase 2, multicenter, randomized, double-blind, double-dummy, placebo-controlled, three-arm trial to be conducted in the United States, Europe, and Asia.NCT00813605·Beverly Hills, California and 66 others

CompletedCombination Chemotherapy Plus Bevacizumab in Treating Patients With Advanced Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006786·Scottsdale, Arizona and 76 others

Active not recruitingTesting a Combination of Vaccines for Cancer Prevention in Lynch SyndromeThis phase IIb trial tests whether Tri-Ad5 in combination with N-803 works to prevent colon and other cancers in participants with Lynch syndrome.NCT05419011·Phoenix, Arizona and 13 others

CompletedGenetic and Environmental Risk Assessment for Colorectal Cancer in Healthy ParticipantsRATIONALE: Evaluating the knowledge and attitudes of healthy participants toward a new diet and gene test for colorectal cancer risk may help doctors improve acceptance of…NCT00087360·Bethesda, Maryland and 3 others

TerminatedCombination Chemotherapy and Cetuximab or Bevacizumab in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy, such as fluorouracil, leucovorin calcium, oxaliplatin, capecitabine, and irinotecan hydrochloride, work in different ways to stop the growth…NCT01280643·Philadelphia, Pennsylvania

CompletedAflibercept Versus Placebo in Combination With Irinotecan and 5-FU in the Treatment of Patients With Metastatic Colorectal Cancer After Failure of an Oxaliplatin Based RegimenThe main objective of the study was to evaluate the effectiveness of aflibercept (versus placebo) in increasing the overall survival in participants with metastatic colorectal…NCT00561470·Birmingham, Alabama and 220 others

CompletedCombination Chemotherapy in Treating Patients With Advanced Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00039611·Anchorage, Alaska and 18 others

CompletedTPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced CancersThis is a phase 1/1b open label, multicenter dose escalation and dose expansion study to investigate the safety, tolerability and anti-tumor activity of TPST-1120, a small…NCT03829436·San Francisco, California and 10 others

CompletedAn Investigational Immuno-therapy Study Of Nivolumab In Combination With Trametinib With Or Without Ipilimumab In Participants With Previously Treated Cancer of the Colon or Rectum That Has SpreadThe purpose of this study is to investigate treatment with nivolumab in combination with trametinib with or without ipilimumab in participants with previously treated cancer of…NCT03377361·Birmingham, Alabama and 46 others

TerminatedRandomized Study Of Sunitinib Plus FOLFOX Versus Bevacizumab Plus FOLFOX In Metastatic Colorectal CancerThis study will compare the safety and efficacy of sunitinib in combination with FOLFOX versus bevacizumab in combination with FOLFOX for the treatment of patients with metastatic…NCT00609622·Fairhope, Alabama and 96 others

TerminatedCombination Chemotherapy Before or After Surgery in Treating Patients With Colorectal Cancer With Liver Metastases That Could Be Removed By SurgeryRATIONALE: Drugs used in chemotherapy work in different ways to kill tumor cells or stop them from growing.NCT01189227·Antioch, California and 282 others

WithdrawnInternet-Based Weight-Loss Program for Colorectal Cancer SurvivorsRATIONALE: A personalized Internet-based weight-loss program may help improve the quality of life for colorectal cancer survivors.NCT01032590·New Brunswick, New Jersey and 1 other

CompletedPrevention of Colorectal Cancer Through Multiomics Blood TestingThe PREEMPT CRC study is a prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples…NCT04369053·Birmingham, Alabama and 147 others

CompletedStudy of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With ColorecThe purpose of this study is to determine whether treatment with Selumetinib (AZD6244) (Hyd-Sulfate) in combination with Irinotecan as a second treatment in patients with K-ras or…NCT01116271·Los Angeles, California and 11 others

CompletedDNA Evaluation of Fragments for Early Interception - Lung Cancer Training Study (DELFI-L101 Study)The primary objective of this study, DELFI-L101, is to train and test classifiers for lung cancer detection using the DELFI assay and other biomarker and clinical features.NCT04825834·Homewood, Alabama and 56 others

CompletedImproving Colorectal Cancer Screening in Racially Diverse Zip Codes Using Navigation and Machine Learning (PCSNaP)The overarching goal of the "PCSNaP" Research Study is to support the Abramson Cancer Center (ACC) of the University of Pennsylvania in carrying out its mission to increase…NCT05383976·Philadelphia, Pennsylvania

CompletedPhase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid TumorsThis is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in…NCT04344795·Aurora, Colorado and 10 others

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Other Conditions in Philadelphia

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma