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Clareo Health | Colorectal Cancer Clinical Trials in Philadelphia | 279 Studies

Clinical Trials Colorectal CancerPhiladelphia

Colorectal Cancer Clinical Trials in Philadelphia

Find 279 clinical trials for colorectal cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 279 trials

CompletedStudy of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer…NCT00063141·Tucson, Arizona and 187 others

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Data from ClinicalTrials.govTerms

Active not recruitingTesting the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF MutationThis phase II trial tests whether adding nivolumab to the usual treatment (encorafenib and cetuximab) works better than the usual treatment alone to shrink tumors in patients with…NCT05308446·Goodyear, Arizona and 285 others

CompletedSWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically RemovedRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002551·Scottsdale, Arizona and 36 others

CompletedCapecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal CancerRATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT00114231·Scottsdale, Arizona and 66 others

RecruitingStudy of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsThis is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity…NCT05176483·Phoenix, Arizona and 121 others

CompletedStudy of Cetuximab, Oxaliplatin, 5-FU/LV Versus Oxaliplatin, 5-FU/LV in Patients With Previously Treated Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to compare overall survival in patients with previously-treated metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer treated…NCT00061815·Little Rock, Arkansas and 38 others

TerminatedEF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerThis clinical trial is studying the amount of EF5 and motexafin lutetium present in tumor cells and/or normal tissues of patients with abdominal (such as ovarian, colon, or…NCT00087191·Philadelphia, Pennsylvania

RecruitingA Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of DiseaseColorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide.NCT07023289·Huntsville, Alabama and 47 others

CompletedEvaluation of the Efficacy of National Cancer Institute's Facing Forward Booklet in the Cancer Community SettingThis study was designed to provide a preliminary evaluation of the efficacy and usability of the 2004 revised version of the booklet, Facing Forward , Life After Cancer Treatment…NCT01440855·Philadelphia, Pennsylvania

CompletedRadiolabeled Monoclonal Antibody Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Recurrent Colorectal Cancer or Pancreatic CancerRATIONALE: Radiolabeled monoclonal antibodies can locate tumor cells and deliver tumor-killing substances to them without harming normal cells.NCT00004087·Belleville, New Jersey and 2 others

Active not recruitingA Study to Evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D MutationThe purpose of this study is to evaluate INCB186748 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D Mutation.NCT06818812·Santa Monica, California and 8 others

CompletedA Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)This was an open-label, nonrandomized, Phase 1/2 study designed to determine the safety, tolerability, and efficacy of epacadostat when given in combination with pembrolizumab and…NCT03085914·Phoenix, Arizona and 15 others

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

TerminatedNeoadjuvant Colorectal Cancer With Unresectable Liver MetastasesThe study was terminated early due to low enrollment with only 2 subjects enrolled and treated after being open for enrollment for over a year.NCT00106054·New York, New York and 1 other

CompletedA Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid TumorsThe purpose of this study is to evaluate the safety profile, tolerability, drug levels, drug effects, and preliminary efficacy of BMS-813160 alone or in combination with either…NCT03184870·Birmingham, Alabama and 39 others

CompletedGefitinib in Treating Patients With Recurrent Metastatic Colorectal CancerRATIONALE: Biological therapies such as gefitinib may interfere with the growth of the tumor cells and slow the growth of recurrent metastatic colorectal cancer.NCT00025350·Chicago, Illinois and 15 others

RecruitingA Study to Evaluate INCB161734 in Participants With Advanced or Metastatic Solid Tumors With KRAS G12D MutationThis study is conducted to determine the safety and tolerability of INCB161734 as a single agent or in combination with other anticancer therapies.NCT06179160·Phoenix, Arizona and 33 others

TerminatedA Trial of an Investigational Drug for the Prevention of Diarrhea Associated With Irinotecan/5FU/Leucovorin Chemotherapy in Previously Untreated Metastatic Colorectal CancerThe study will combine a new investigational drug with standard anti-cancer drugs for the treatment of advanced colorectal cancer.NCT00040391·Little Rock, Arkansas and 27 others

RecruitingA Study of GSK5764227 in Combination With Standard of Care (SoC) or Other Agents in Participants With Advanced Solid TumorsThe goal of this clinical trial is to test a new medicine called GSK5764227, which delivers a toxin directly to cancer cells to destroy them while sparing healthy cells.NCT07277270·Reunion, Florida and 21 others

CompletedTAS-102, Irinotecan, and Bevacizumab for the Treatment of Pre-treated Metastatic or Unresectable Colorectal Cancer, the TABAsCO StudyThis phase II trial studies how well TAS-102, irinotecan, and bevacizumab work in treating patients with pre-treated colorectal cancer that has spread to other places in the body…NCT04109924·Tampa, Florida and 3 others

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