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Clareo Health | Colorectal Cancer Clinical Trials in Pennsylvania | 498 Studies

Clinical Trials Colorectal CancerPennsylvania

Colorectal Cancer Clinical Trials in Pennsylvania

Find 498 clinical trials for colorectal cancer near Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 498 trials

CompletedCombination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal CancerRATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.NCT00613080·Mobile, Alabama and 119 others

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Data from ClinicalTrials.govTerms

CompletedOxaliplatin in Treating Patients With Recurrent Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00017082·Washington D.C., District of Columbia and 9 others

CompletedINCB106385 Alone or in Combination With Immunotherapy in Advanced Solid TumorsThis is a multicenter, open-label, dose-escalation/dose-expansion Phase 1 clinical study to investigate the safety, tolerability, PK profile, pharmacodynamics, and preliminary…NCT04580485·West Hollywood, California and 26 others

CompletedA Dose Escalation/Expansion Study of ERAS-601 in Patients With Advanced or Metastatic Solid Tumors* To evaluate the safety and tolerability of escalating doses of ERAS-601 when administered as a monotherapy and in combination with other cancer therapies in study participants…NCT04670679·Birmingham, Alabama and 13 others

CompletedPatient-Reported Outcomes in Long-Term Survivors of Colon and Rectal CancersRATIONALE: Learning about quality of life, symptoms, and health behaviors in colorectal cancer survivors may help to determine the long-term effects of colon and rectal cancer…NCT00410579·Aurora, Colorado and 199 others

CompletedStudy With AG-013736 Combined With Chemotherapy And Bevacizumab In Patients With Metastatic Colorectal CancerTo determine the safety and efficacy of AG-013736 in combination with other standard of care medication in patients with first line metastatic colorectal cancer.NCT00460603·Daphne, Alabama and 105 others

CompletedA Physician-Based Trial to Increase Colorectal Cancer Screening in ChineseThe objective of this study is to test whether a culturally-tailored in-office based intervention have impact on increasing Chinese physician's recommendation of colorectal cancer…NCT01289288·Washington D.C., District of Columbia and 1 other

RecruitingA Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal CancerThe purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of…NCT07284849·Mobile, Alabama and 279 others

RecruitingStudy of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid TumorsThe investigational drug to be studied in this protocol, BCA101, is a first-in-class compound that targets both EGFR with TGFβ.NCT04429542·La Jolla, California and 19 others

Active not recruitingStudy of LY3537982 in Cancer Patients With a Specific Genetic Mutation (KRAS G12C)The purpose of this study is to find out whether the study drug, LY3537982, is safe and effective in cancer patients who have a specific genetic mutation (KRAS G12C).NCT04956640·Birmingham, Alabama and 48 others

TerminatedTrilaciclib, a CDK 4/6 Inhibitor, in Patients Receiving FOLFOXIRI/Bevacizumab for Metastatic Colorectal Cancer (mCRC):This was a randomized, double-blind, placebo-controlled, global, multicenter, Phase 3 trial evaluating the impact of trilaciclib on myelopreservation and anti-tumor efficacy when…NCT04607668·Tucson, Arizona and 81 others

UnknownPROSPECT: Chemotherapy Alone or Chemotherapy Plus Radiation Therapy in Treating Patients With Locally Advanced Rectal Cancer Undergoing SurgeryThe standard treatment for locally advanced rectal cancer involves chemotherapy and radiation, known as 5FUCMT, (the chemotherapy drugs 5-fluorouracil/capecitabine and radiation…NCT01515787·Birmingham, Alabama and 1072 others

CompletedCombination Chemotherapy in Treating Patients With Liver Metastases From Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.NCT00002716·Cedar Rapids, Iowa and 13 others

CompletedPatients With Metastatic Colorectal Cancer Treated With Regorafenib or Placebo After Failure of Standard TherapyThis is a randomized, double-blind, placebo-controlled multi-center phase III study to evaluate efficacy and safety of regorafenib in patients with metastatic colorectal cancer…NCT01103323·Beverly Hills, California and 170 others

RecruitingSKL35501 With SKL35502 Imaging in Adults With NTSR1 Positive Advanced Solid TumorsThis Phase 1, open-label study will evaluate two investigational radiopharmaceuticals in adults with selected advanced or metastatic solid tumors.NCT07812805·Glen Burnie, Maryland and 4 others

CompletedVaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic CancerPhase I trial to study the effectiveness of vaccine therapy with or without sargramostim in treating patients who have advanced or metastatic cancer.NCT00028496·Philadelphia, Pennsylvania

RecruitingStudy of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsThis study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated…NCT06128551·Duarte, California and 55 others

CompletedhTERT Immunotherapy Alone or in Combination With IL-12 DNA Followed by Electroporation in Adults With Solid Tumors at High Risk of RelapseThis is a Phase I, open label study to evaluate the safety, tolerability, and immunogenicity of INO-1400 or INO-1401 alone or in combination with INO-9012, delivered by…NCT02960594·Detroit, Michigan and 5 others

TerminatedA Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid TumorsThis is a first in human (FIH) 2-part study using ACTM-838 in patients with advanced solid tumors resistant to standard of care treatment.NCT06336148·Los Angeles, California and 4 others

CompletedA Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)The goal of this clinical trial is to test the safety and efficacy of KVA12123 alone or combined with pembrolizumab in patients with advanced solid tumors.NCT05708950·Santa Monica, California and 6 others

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Other Conditions in Pennsylvania

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