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Clareo Health | Colorectal Cancer Clinical Trials in Pennsylvania | 498 Studies

Clinical Trials Colorectal CancerPennsylvania

Colorectal Cancer Clinical Trials in Pennsylvania

Find 498 clinical trials for colorectal cancer near Pennsylvania. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 498 trials

CompletedStudy of Irinotecan and Cetuximab Versus Irinotecan as Second-Line Treatment in Patients With Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to determine whether overall survival is prolonged in subjects with metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer…NCT00063141·Tucson, Arizona and 187 others

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Data from ClinicalTrials.govTerms

Active not recruitingTesting the Addition of Nivolumab to Standard Treatment for Patients With Metastatic or Unresectable Colorectal Cancer That Have a BRAF MutationThis phase II trial tests whether adding nivolumab to the usual treatment (encorafenib and cetuximab) works better than the usual treatment alone to shrink tumors in patients with…NCT05308446·Goodyear, Arizona and 285 others

CompletedSWOG-9304 Chemotherapy Plus Radiation Therapy in Treating Patients With Rectal Cancer That Has Been Surgically RemovedRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002551·Scottsdale, Arizona and 36 others

Active not recruitingA Study of TSR-022 in Participants With Advanced Solid Tumors (AMBER)This is a first-in-human study evaluating the anti-T cell immunoglobulin and mucin containing protein-3 (TIM-3) antibody TSR-022.NCT02817633·Goodyear, Arizona and 88 others

CompletedVaccine Therapy in Treating Patients With Colorectal Cancer Metastatic to the LiverRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00033748·Anniston, Alabama and 74 others

RecruitingTesting the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, ERASur TrialThis phase III trial compares the addition of total ablative therapy to the usual systemic therapy versus the usual systemic therapy alone in treating patients with advanced…NCT05673148·Kingman, Arizona and 188 others

RecruitingBeamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has SpreadThis study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery.NCT06324357·Cerritos, California and 104 others

WithdrawnEpacadostat in Combination With Pembrolizumab and Azacitidine in Subjects With Metastatic Colorectal CancerTrial Design This is an open label, single-arm, phase IB/II trial to evaluate the safety, tolerability and anti-tumor efficacy of epacadostat (INCB024360) in combination with…NCT03182894·Pittsburgh, Pennsylvania

CompletedCapecitabine, Oxaliplatin, and Radiation Therapy in Treating Patients Who Are Undergoing Surgery for Stage I Rectal CancerRATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT00114231·Scottsdale, Arizona and 66 others

RecruitingStudy of Zanzalintinib in Combination With Immuno-Oncology or Other Agents in Participants With Solid TumorsThis is a multicenter Phase 1b, open label, dose-escalation and cohort-expansion study, evaluating the safety, tolerability, pharmacokinetics (PK), preliminary antitumor activity…NCT05176483·Phoenix, Arizona and 121 others

CompletedSurgery With or Without Chemotherapy and Radiation Therapy in TreatingPatients With Stage I Rectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00023751·Anniston, Alabama and 179 others

CompletedLower or Standard Dose Regorafenib in Treating Patients With Refractory Metastatic Colorectal CancerThis randomized phase II trial studies how well lower-dose compared to standard dose regorafenib works in treating patients with colorectal cancer that has spread from the primary…NCT02368886·Phoenix, Arizona and 21 others

CompletedStudy of Cetuximab, Oxaliplatin, 5-FU/LV Versus Oxaliplatin, 5-FU/LV in Patients With Previously Treated Metastatic, EGFR-Positive Colorectal CancerThe purpose of this study is to compare overall survival in patients with previously-treated metastatic, epidermal growth factor receptor (EGFR)-positive colorectal cancer treated…NCT00061815·Little Rock, Arkansas and 38 others

CompletedSafeHeal Diverting Ileostomy Pivotal StudyThis SafeHeal study is designed to assess the overall safety of the low anterior resection (LAR) standard of care cancer treatment by establishing a definition of major…NCT06152276·Los Angeles, California and 21 others

TerminatedEF5 and Motexafin Lutetium in Detecting Tumor Cells in Patients With Abdominal or Non-Small Cell Lung CancerThis clinical trial is studying the amount of EF5 and motexafin lutetium present in tumor cells and/or normal tissues of patients with abdominal (such as ovarian, colon, or…NCT00087191·Philadelphia, Pennsylvania

TerminatedA Study to Investigate LYL845 in Adults With Solid TumorsThis is an open-label, multi-center, dose-escalation study with expansion cohorts, designed to evaluate the safety and anti-tumor activity of LYL845, an epigenetically…NCT05573035·Sacramento, California and 17 others

RecruitingA Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of DiseaseColorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide.NCT07023289·Huntsville, Alabama and 47 others

CompletedEvaluation of the Efficacy of National Cancer Institute's Facing Forward Booklet in the Cancer Community SettingThis study was designed to provide a preliminary evaluation of the efficacy and usability of the 2004 revised version of the booklet, Facing Forward , Life After Cancer Treatment…NCT01440855·Philadelphia, Pennsylvania

CompletedRadiolabeled Monoclonal Antibody Therapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Metastatic or Recurrent Colorectal Cancer or Pancreatic CancerRATIONALE: Radiolabeled monoclonal antibodies can locate tumor cells and deliver tumor-killing substances to them without harming normal cells.NCT00004087·Belleville, New Jersey and 2 others

CompletedA Study of Dulanermin Administered in Combination With Camptosar®/Erbitux® Chemotherapy or FOLFIRI (With or Without Bevacizumab) in Subjects With Previously Treated Metastatic Colorectal CancerThis study will assess the safety and pharmacokinetics of adding dulanermin to Camptosar®/Erbitux® or the FOLFIRI regimen (Camptosar®, 5-FU, and leucovorin) plus bevacizumab (only…NCT00671372·Los Angeles, California and 9 others

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