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Clinical Trials Colorectal CancerNashville

Colorectal Cancer Clinical Trials in Nashville

Find 359 clinical trials for colorectal cancer near Nashville, Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Nashville

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 301-320 of 359 trials

CompletedS1406 Phase II Study of Irinotecan and Cetuximab With or Without Vemurafenib in BRAF Mutant Metastatic Colorectal CancerThis randomized phase II trial studies how well irinotecan hydrochloride and cetuximab with or without vemurafenib works in treating patients with colorectal cancer that has…NCT02164916·Anchorage, Alaska and 762 others

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Data from ClinicalTrials.govTerms

TerminatedA Study of Rivoceranib and Trifluridine/Tipiracil for Metastatic Colorectal Cancer (mCRC)The purpose of this study is to determine the recommended Phase 2 dose (RP2D) of rivoceranib when used in combination with trifluridine/tipiracil in participants with mCRC and to…NCT04073615·Sarasota, Florida and 3 others

Active not recruitingFirst in Human Study of TORL-3-600 in Participants With Advanced CancerThis first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-3-600 in patients with advanced cancerNCT05948826·Fullerton, California and 8 others

RecruitingGastrointestinal Biomarkers in Tissue and Biological Fluid Samples From Colorectal Cancer PatientsRATIONALE: Studying samples of tissue, blood, urine, stool, and other biological fluids from patients with cancer and from healthy volunteers undergoing colonoscopy or endoscopy…NCT00899626·Nashville, Tennessee and 1 other

TerminatedA Study of Fruquintinib in Combination With Tislelizumab in Advanced Solid TumorsThis is an open-label, multi-center, non-randomized, Phase 1b/2 study to assess the safety and efficacy of fruquintinib in combination with tislelizumab in patients with locally…NCT04577963·Phoenix, Arizona and 15 others

CompletedA Study of Prexasertib (LY2606368) in Combination With Ralimetinib in Participants With Advanced or Metastatic CancerThe main purpose of this study is to evaluate the safety of the study drug prexasertib in combination with ralimetinib in participants with advanced or metastatic cancer.NCT02860780·Charlotte, North Carolina and 2 others

UnknownPemigatinib for the Treatment of Metastatic or Unresectable Colorectal Cancer Harboring FGFR AlterationsThis phase II trial studies how well pemigatinib works in treating patients with colorectal cancer with mutations (alterations) in a FGFR gene and that has spread to other places…NCT04096417·Scottsdale, Arizona and 5 others

RecruitingSYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and RegistryInternational registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool…NCT03452774·Birmingham, Alabama and 67 others

TerminatedA Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal CancerA phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm tested and to identify recommended…NCT04294160·Los Angeles, California and 17 others

TerminatedStudy of RO7515629 in Participants With HLA-G Positive Solid TumorsThe main purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, immune response and preliminary anti-tumor activity of RO7515629 alone in participants…NCT05769959·Denver, Colorado and 1 other

RecruitingA Study of ART0380 for the Treatment of Advanced or Metastatic Solid TumorsThis clinical trial is evaluating a drug called ART0380 in participants with advanced or metastatic solid tumors.NCT04657068·Birmingham, Alabama and 87 others

RecruitingTesting Pump Chemotherapy in Addition to Standard of Care Chemotherapy Versus Standard of Care Chemotherapy Alone for Patients With Unresectable Colorectal Liver Metastases: The PUMP TrialThis phase III trial compares hepatic arterial infusion (HAI) (pump chemotherapy) in addition to standard of care chemotherapy versus standard of care chemotherapy alone in…NCT05863195·Birmingham, Alabama and 61 others

CompletedFOLFOXIRI Plus Panitumumab Patients With Metastatic KRAS Wild-Type Colorectal Cancer With Liver Metastases OnlyIn this Phase II study the investigators plan to determine the overall response rate (ORR) of the combination of FOLFOXIRI plus panitumumab as first-line treatment of patients…NCT01226719·Jonesboro, Arkansas and 14 others

CompletedPhase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal CancerTo determine the effect of ABT-869 plus mFOLFOX6 compared to bevacizumab plus mFOLFOX6 on disease progression in advanced colorectal cancer.NCT00707889·Chapel Hill, North Carolina and 45 others

CompletedA Study of LY3214996 Administered Alone or in Combination With Other Agents in Participants With Advanced/Metastatic CancerThe purpose of this study is to determine the safety of an extracellular signal regulated kinase (ERK1/2) inhibitor LY3214996 administered alone or in combination with other…NCT02857270·Washington D.C., District of Columbia and 12 others

CompletedA Study in Second Line Metastatic Colorectal CancerThe purpose of this study is to compare overall survival in participants with metastatic colorectal cancer treated with either ramucirumab and FOLFIRI or placebo and FOLFIRI.NCT01183780·Sedona, Arizona and 212 others

CompletedA Study of ELI-002 in Subjects With KRAS Mutated Pancreatic Ductal Adenocarcinoma (PDAC) and Other Solid TumorsThis is a Phase 1 study to assess the safety and efficacy of ELI-002 immunotherapy (a lipid-conjugated immune-stimulatory oligonucleotide \[Amph-CpG-7909\] plus a mixture of…NCT04853017·Duarte, California and 9 others

RecruitingTesting the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable CancersThis phase I trial tests the safety, side effects, and best dose of ZEN003694 in combination with the usual treatment with capecitabine in treating patients with cancer that has…NCT05803382·Irvine, California and 21 others

CompletedA Study of Personalized Neoantigen Cancer VaccinesThe purpose of this study is 1) to evaluate the feasibility of manufacturing a patient-specific neoantigen cancer vaccine, which involves predicting the patient's neoantigens and…NCT03794128·Chicago, Illinois and 4 others

RecruitingStudy of Dato-DXd as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Tumours (TROPION-PanTumor03)TROPION-PanTumor03 will investigate the safety, tolerability, and anti-tumour activity of Datopotamab Deruxtecan (Dato-DXd) as Monotherapy and in Combination with Anticancer…NCT05489211·Los Angeles, California and 95 others

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