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Clareo Health | Colorectal Cancer Clinical Trials in Massachusetts | 399 Studies

Clinical Trials Colorectal CancerMassachusetts

Colorectal Cancer Clinical Trials in Massachusetts

Find 399 clinical trials for colorectal cancer near Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 399 trials

CompletedTrial of MEK Inhibitor and PI3K/mTOR Inhibitor in Subjects With Locally Advanced or Metastatic Solid TumorsThis research trial is testing a combination of two experimental drugs, MSC1936369B (Mitogen-activated protein extracellular signal-regulated kinase (MEK) Inhibitor) and SAR245409…NCT01390818·Scottsdale, Arizona and 7 others Active not recruitingASPirin Intervention for the REDuction of Colorectal Cancer RiskThis research study is investigating the use of aspirin as a potential chemopreventive agent to reduce risk of colorectal cancerNCT02394769·Boston, Massachusetts TerminatedA Study to Learn About the Study Medicine PF-07985045 When Given Alone or With Other Anti-cancer Therapies in People With Advanced Solid Tumors That Have a Change in a Gene.The purpose of this study is to learn about the safety and effects of the study medicine when given alone or together with other anti-cancer therapies.NCT06704724·Fayetteville, Arkansas and 12 others

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Data from ClinicalTrials.govTerms

TerminatedStudy of BDC-3042 as Single Agent and in Combination With Cemiplimab in Patients With Advanced MalignanciesA first-in-human study using BDC-3042 as a single agent and in combination with cemiplimab in patients with advanced malignanciesNCT06052852·Palo Alto, California and 5 others

Active not recruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid TumorsThis is a first-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of enzelkitug when administered as a single agent and in…NCT05581004·San Francisco, California and 35 others

CompletedEffects of STM 434 Alone or in Combination With Liposomal Doxorubicin in Patients With Ovarian Cancer or Other Advanced Solid TumorsThis is a Phase I study to test the safety, pharmacokinetics and effectiveness of STM 434 alone, or in combination with liposomal doxorubicin, in patients with ovarian cancer or…NCT02262455·Boston, Massachusetts and 3 others

CompletedA Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced CancersThe purpose of this study was to evaluate the safety and tolerability of escalating doses of the MM-121 plus cetuximab and the MM-121 plus cetuximab plus irinotecan combination.NCT01451632·San Francisco, California and 3 others

CompletedA Study of BMS-813160 in Combination With Chemotherapy or Nivolumab in Participants With Advanced Solid TumorsThe purpose of this study is to evaluate the safety profile, tolerability, drug levels, drug effects, and preliminary efficacy of BMS-813160 alone or in combination with either…NCT03184870·Birmingham, Alabama and 39 others

CompletedGenetic Trial to Study Diarrhea in Patients With Stage III Colon Cancer Who Are Receiving ChemotherapyRATIONALE: Genetic testing may help predict how patients will respond to chemotherapy drugs and may help doctors plan more effective treatment with fewer side effects.NCT00048971·Anniston, Alabama and 83 others

CompletedA Dose Escalation and Cohort Expansion Study of Anti-CD27 (Varlilumab) and Anti-PD-1 (Nivolumab) in Advanced Refractory Solid TumorsThis is a study to determine the clinical benefit (how well the drug works), safety, and tolerability of combining varlilumab and nivolumab (also known as Opdivo® , BMS-936558).NCT02335918·Tucson, Arizona and 18 others

RecruitingA Trial to Evaluate the Safety and Activity of Fruquintinib in Minority Populations With Advanced, Previously Treated Colorectal CancerHigh blood pressure (hypertension) is a known side effect of the treatment with fruquintinib.NCT06562543·Birmingham, Alabama and 44 others

CompletedTucatinib Plus Trastuzumab in Patients With HER2+ Colorectal CancerThis trial studies how well the drug tucatinib works when given with trastuzumab and when given by itself.NCT03043313·Birmingham, Alabama and 55 others

Active not recruitingStudy of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid MalignanciesThis research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has…NCT04644068·Boston, Massachusetts and 67 others

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

RecruitingAMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsThe purpose of this first-in-human study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AMG 410 when…NCT07094113·Duarte, California and 38 others

RecruitingA Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)Researchers are looking for a better way to treat people who have solid tumors with HER2-activating mutations.NCT06760819·Birmingham, Alabama and 53 others

TerminatedStudy of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intratumorally in…NCT04144140·New Haven, Connecticut and 12 others

CompletedStudy of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects With Gastrointestinal, Pancreatic, or Colorectal CancerStudy of Romiplostim for Chemotherapy-induced Thrombocytopenia in Adult Subjects with Gastrointestinal, Pancreatic, or Colorectal CancerNCT03362177·Jonesboro, Arkansas and 116 others

CompletedComputer Aided Detection of Polyps in the ColonThe purpose of this study is to examine the role of an automatic polyp detection software (henceforth referred to as the research software) as a support system during colonoscopy…NCT03925337·Chicago, Illinois and 3 others

CompletedLaparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon CancerRATIONALE: Less invasive types of surgery may help reduce the number of side effects and improve recovery.NCT00002575·Huntsville, Alabama and 157 others

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Other Conditions in Massachusetts

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