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Clareo Health | Colorectal Cancer Clinical Trials in Massachusetts | 399 Studies

Clinical Trials Colorectal CancerMassachusetts

Colorectal Cancer Clinical Trials in Massachusetts

Find 399 clinical trials for colorectal cancer near Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 399 trials

RecruitingStereotactic Brain-directed Radiation With or Without Aguix Gadolinium-Based Nanoparticles in Brain MetastasesThe purpose of this study is to determine whether AGuIX (Activation and Guidance of Irradiation by X-ray) gadolinium-based nanoparticles make radiation work more effectively in…NCT04899908·Boston, Massachusetts and 1 other CompletedHepatic Arterial Infusion With Floxuridine and Systemic Irinotecan After Surgery in Treating Patients With Hepatic (Liver) Metastases From Colorectal CancerRATIONALE: Drugs used in chemotherapy such as floxuridine and irinotecan use different ways to stop tumor cells from dividing so they stop growing or die.NCT00063960·Little Rock, Arkansas and 9 others CompletedStudy of Bevacizumab + mFOLFOX6 Versus Bevacizumab + FOLFIRI With Biomarker Stratification in Participants With Previously Untreated Metastatic Colorectal Cancer (mCRC)This will be a randomized, open-label, multicenter, Phase II study with primary objectives to assess whether expression of select chemotherapy markers is associated with…NCT01374425·Birmingham, Alabama and 78 others

Colorectal Cancer Trials in Other Cities

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Data from ClinicalTrials.govTerms

TerminatedGenetic Testing in Screening Patients With Metastatic or Unresectable Colon or Rectal Cancer for a COLOMATE TrialThis trial screens patients with colon or rectal cancer that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable) for genetic…NCT03765736·Scottsdale, Arizona and 17 others

Not yet recruitingPhase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or MetastaticThis study is a first-in-human (FIH) Phase 1 open-label, multicenter study including three parts: * Part 1A is a dose escalation of STRO-006 monotherapy in selected tumor types…NCT07807345·La Jolla, California and 6 others

Active not recruitingDuloxetine to Prevent Oxaliplatin-Induced Peripheral Neuropathy in Patients With Stage II-III Colorectal CancerThis phase II/III trial studies the best dose of duloxetine and how well it works in preventing pain, tingling, and numbness (peripheral neuropathy) caused by treatment with…NCT04137107·Birmingham, Alabama and 792 others

TerminatedA Safety and Activity Study of SBT6050 in Combination With Other HER2-directed Therapies for HER2-positive CancersThis study is designed to assess the safety and preliminary activity of SBT6050 in combination with trastuzumab deruxtecan (Part 1) or tucatinib plus trastuzumab +/- capecitabine…NCT05091528·Boston, Massachusetts

CompletedA Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsThis is a first-in-human, open-label, dose escalation study to evaluate the safety and tolerability of pegilodecakin in participants with advanced solid tumors, dosed daily…NCT02009449·Los Angeles, California and 9 others

TerminatedA Phase 1b Trial of ATRC-101 in Adults With Advanced Solid MalignanciesATRC-101-A01 is a Phase 1b, open-label dose escalation and expansion trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a…NCT04244552·Phoenix, Arizona and 18 others

CompletedStudy of Bevacizumab, Erlotinib, FOLFOX for Patients With Untreated Metastatic Colorectal CancerDespite recent advances, most patients with advanced colorectal cancer continue to have a poor prognosis.NCT00116506·Boston, Massachusetts and 2 others

RecruitingA Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid TumorsThe goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations.NCT06244771·La Jolla, California and 25 others

CompletedExercise and Metformin in Colorectal and Breast Cancer SurvivorsMetformin is a medication that is commonly used in the treatment of diabetes.NCT01340300·New Haven, Connecticut and 1 other

CompletedBlood Collection Sub-Study for CRC Screening in Individuals 45-49 at Average Risk for CRC.The primary objective of this sub-study, 2018-10B, is to collect blood specimens to assess new biomarkers for the detection of Colorectal Cancer (CRC).NCT03741166·Phoenix, Arizona and 36 others

Active not recruitingStudy of JDQ443 in Patients With Advanced Solid Tumors Harboring the KRAS G12C MutationThis is a phase Ib/II open label study.NCT04699188·Atlanta, Georgia and 37 others

TerminatedStudy of CB-839 (Telaglenastat) in Combination With Talazoparib in Patients With Solid TumorsThis is a Phase 1b/2 study to determine the recommended phase 2 dose (RP2D), safety and tolerability, pharmacokinetics (PK) and clinical activity of the glutaminase inhibitor…NCT03875313·Birmingham, Alabama and 8 others

CompletedOpen Pilot Trial of a Mind-Body Sexual Well-Being Intervention for Female GI Cancer SurvivorsThe primary goal of this protocol is to conduct an open pilot to collect initial quantitative and qualitative feedback on the intervention that the investigators are developing.NCT06331403·Boston, Massachusetts

CompletedCombination Chemotherapy and Intensity-Modulated Radiation Therapy in Treating Patients Undergoing Surgery for Locally Advanced Rectal CancerRATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.NCT00613080·Mobile, Alabama and 119 others

TerminatedA Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal CancerA phase Ib, open-label platform study of select drug combinations chosen in order to characterize safety and tolerability of each treatment arm tested and to identify recommended…NCT04294160·Los Angeles, California and 17 others

CompletedA Phase 1a/b Dose Escalation Study of the Safety, Pharmacokinetics, and Pharmacodynamics of OMP-131R10This is an open-label Phase 1a/b dose-escalation study to assess the safety, tolerability, and PK of OMP-131R10 as a single agent for advanced solid tumors and in subjects with…NCT02482441·San Francisco, California and 6 others

CompletedPerioperative Geriatrics Intervention for Older Cancer Patients Undergoing Surgical ResectionThe purpose of this research study is to addresses the challenge of managing the unique perioperative needs of older cancer patients undergoing surgical resection.NCT02810652·Boston, Massachusetts

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Other Conditions in Massachusetts

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