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Clareo Health | Colorectal Cancer Clinical Trials in Georgia | 254 Studies

Clinical Trials Colorectal CancerGeorgia

Colorectal Cancer Clinical Trials in Georgia

Find 254 clinical trials for colorectal cancer near Georgia. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Georgia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 21-40 of 254 trials

RecruitingA Study to Evaluate the Efficacy and Safety of Standard-of-Care Chemotherapy and Bevacizumab With or Without INCA33890 in the First-Line Treatment of Metastatic Microsatellite Stable Colorectal CancerThe purpose of this study is to evaluate the efficacy and safety of standard-of-care chemotherapy and bevacizumab with or without INCA33890 in the first-line treatment of…NCT07284849·Mobile, Alabama and 296 others

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Data from ClinicalTrials.govTerms

CompletedPembrolizumab Combined With Itacitinib (INCB039110) and/or Pembrolizumab Combined With INCB050465 in Advanced Solid TumorsThis is an open-label, multicenter, Phase 1b platform study in subjects with advanced or metastatic solid tumors (Part 1a) and subjects with selected solid tumors (Part 1b and…NCT02646748·San Francisco, California and 16 others

RecruitingSafely Optimizing Body Weight With Mifomelatide (TCMCB07) in Patients With Newly Diagnosed Colorectal Cancer (CRC) or Pancreatic Ductal Adenocarcinoma (PDAC) Undergoing ChemotherapyThis is a randomized, double-blind, placebo-controlled basket trial evaluating mifomelatide (TCMCB07) administered daily by subcutaneous (SC) injection in up to 120 patients.NCT06937177·Tucson, Arizona and 25 others

CompletedA Study of Irinotecan Plus Cetuximab With or Without Enzastaurin in Participants With Colorectal CancerTo see how well enzastaurin in combination with irinotecan and cetuximab works versus irinotecan and cetuximab in participants who have progressed within 3 months.NCT00437268·Casa Grande, Arizona and 19 others

RecruitingA Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid TumorsThis is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent…NCT03526835·La Jolla, California and 53 others

CompletedA Phase 1/2 Study of INCB001158 in Combination With Chemotherapy in Subjects With Solid TumorsThe purpose of this open-label nonrandomized Phase 1/2 study is to evaluate INCB001158 in combination with chemotherapy in participants with advanced/metastatic solid tumors.NCT03314935·Birmingham, Alabama and 9 others

Active not recruitingStudy of Cabozantinib Alone or in Combination With Atezolizumab to Subjects With Locally Advanced or Metastatic Solid TumorsThis is a multicenter Phase 1b, open-label study to assess safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of cabozantinib taken in combination with…NCT03170960·Gilbert, Arizona and 123 others

Active not recruitingSafety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLCThis is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single…NCT04140526·Springdale, Arkansas and 36 others

CompletedSotorasib and Panitumumab Versus Investigator's Choice for Participants With Kirsten Rat Sarcoma (KRAS) p.G12C MutationThe aim of the study is to compare progression-free survival (PFS) in previously treated participants with Kirsten rat sarcoma (KRAS) p.G12C mutated colorectal cancer (CRC)…NCT05198934·Birmingham, Alabama and 104 others

CompletedBevacizumab and Oxaliplatin Combined With Irinotecan or Leucovorin and Fluorouracil in Treating Patients With Metastatic or Recurrent Colorectal CancerRATIONALE: Drugs used in chemotherapy, such as oxaliplatin, irinotecan, leucovorin, and fluorouracil, work in different ways to stop the growth of tumor cells, either by killing…NCT00098787·Greenbrae, California and 109 others

No longer availableRegorafenib in Subjects With Metastatic Colorectal Cancer (CRC) Who Have Progressed After Standard TherapyThis is a phase III B, prospective, interventional, open-label, single-arm, multicenter study to provide regorafenib to subjects diagnosed with metastatic colorectal cancer who…NCT01538680·Duarte, California and 206 others

CompletedNivolumab and Metformin in Patients With Treatment Refractory MSS Colorectal CancerThis phase II trial studies how well nivolumab and metformin work in treating patients with microsatellite stable (MSS) stage IV colorectal cancer that has not responded to…NCT03800602·Atlanta, Georgia and 2 others

CompletedA Multicenter Phase 2 Study of CI-1040 in Patients With Advanced Nonsmall-Cell Lung, Breast, Colon and Pancreatic CancerCI-1040 is an experimental drug that is being tested in patients who have advanced colorectal and lung cancer who failed no more than one prior chemotherapy regimen, breast cancer…NCT00034827·Birmingham, Alabama and 29 others

CompletedA Study Combining FOLFOX or FOLFIRI With AG-013736 or Bevacizumab (Avastin) in Patients With Metastatic Colorectal Cancer After Failure Of One First Line RegimenThe study is designed to demonstrate that the combination of AG-013736 with either FOLFIRI or FOLFOX is superior to FOLFIRI or FOLFOX in combination with bevacizumab (Avastin) in…NCT00615056·Mobile, Alabama and 82 others

CompletedSWOG-S9635 Fluorouracil Plus Ethynyluracil in Advanced Colorectal Cancer Not Responded to FluorouracilRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003254·Mobile, Alabama and 85 others

CompletedQUILT-2.018: Safety & Efficacy of FOLFIRI With AMG 479 or AMG 655 vs FOLFIRI Alone in KRAS-mutant Metastatic Colorectal CarcinomaThis is a phase 2, multicenter, randomized, double-blind, double-dummy, placebo-controlled, three-arm trial to be conducted in the United States, Europe, and Asia.NCT00813605·Beverly Hills, California and 66 others

RecruitingPost-Market Study of the Signia Circular Stapler With Tri-Staple Technology in Left-sided Colon, Sigmoid, and Rectal ResectionsThe purpose of this study is to evaluate the safety and performance of the Signia™ power handle, Signia™ circular adapter, and Signia™ Tri-Staple™ 2.0 circular reloads (hereafter…NCT07351071·New Haven, Connecticut and 9 others

CompletedA Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal CancerThis is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard…NCT02753127·Birmingham, Alabama and 210 others

TerminatedPhase 1 Combination Study of MM-151 With MM-121, MM-141, or TrametinibThis is a Phase 1 open-label, dose-escalation trial using "3+3" design, evaluating MM-151 co-administration with MM-121, MM-141, and trametinib at varying dose levels.NCT02538627·Aurora, Colorado and 4 others

CompletedGenetic Study of Young Patients With Colorectal CancerRATIONALE: Identifying gene mutations (microsatellite instability) may allow doctors to plan effective treatment for patients who develop colorectal cancer at an early age.NCT00044967·Mobile, Alabama and 72 others

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