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Clareo Health | Colorectal Cancer Clinical Trials in Florida | 551 Studies

Clinical Trials Colorectal CancerFlorida

Colorectal Cancer Clinical Trials in Florida

Find 551 clinical trials for colorectal cancer near Florida. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Florida

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 241-260 of 551 trials

CompletedStudy of the Safety, Tolerability and Efficacy of KPT-8602 in Participants With Relapsed/Refractory Cancer IndicationsThis is a first-in-human, multi-center, open-label clinical study with separate dose escalation (Phase 1) and expansion (Phase 2) stages to assess preliminary safety…NCT02649790·Los Angeles, California and 45 others

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Data from ClinicalTrials.govTerms

RecruitingThe Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)The Phase 2 monotherapy portion of this study is currently enrolling and will evaluate the efficacy and safety of PC14586 (INN rezatapopt) in participants with locally advanced or…NCT04585750·Irvine, California and 76 others

CompletedOnvansertib in Combination With FOLFIRI and Bevacizumab for Second Line Treatment of Metastatic Colorectal Cancer Patients With a KRAS MutationThe purpose of the Phase 1b/2 study is to determine the safety and efficacy of Onvansertib, administered orally, daily on Day 1-5 and Day 15-19 of each 28-day cycle, in…NCT03829410·Phoenix, Arizona and 6 others

RecruitingA First-in-Human Trial of BLU-924 (SAR449336) in Advanced Solid Tumors Harboring KRAS MutationsA first in human study to evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of BLU-924 / SAR449336, a pan-KRAS inhibitor, in participants with advanced…NCT07629960·Sarasota, Florida and 15 others

CompletedStudy of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal CancerThis is a multicenter, randomized, open-label, 3-arm Phase 3 study to evaluate encorafenib + cetuximab plus or minus binimetinib versus Investigator's choice of either…NCT02928224·Phoenix, Arizona and 417 others

RecruitingAn Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.A multi-center evaluation of NGM120 in a randomized, double-blind, placebo-controlled study in participants with colorectal cancer who have cancer cachexia.NCT07033026·Los Angeles, California and 27 others

CompletedBlood Sample Collection to Evaluate Biomarkers in Subjects With Untreated Solid TumorsThe primary objective of this study is to obtain de-identified, clinically characterized, whole blood specimens to evaluate biomarkers associated with cancer for diagnostic assay…NCT03662204·Phoenix, Arizona and 118 others

RecruitingA Study to Test DSP107 in Combination With Atezolizumab in Comparison With Fruquintinib as a New Treatment for Colorectal Cancer.This clinical study is testing whether a new combination of medicines (DSP107 and atezolizumab) is more effective and safer than an existing treatment (fruquintinib) for people…NCT07235293·Aurora, Colorado and 17 others

CompletedGenetic Trial to Study Diarrhea in Patients With Stage III Colon Cancer Who Are Receiving ChemotherapyRATIONALE: Genetic testing may help predict how patients will respond to chemotherapy drugs and may help doctors plan more effective treatment with fewer side effects.NCT00048971·Anniston, Alabama and 83 others

Active not recruitingRadiation Therapy and Fluorouracil With or Without Combination Chemotherapy Followed by Surgery in Treating Patients With Stage II or Stage III Rectal CancerRATIONALE: Radiation therapy uses high-energy x-rays to kill tumor cells.NCT00335816·Concord, California and 14 others

CompletedStudy of Selumetinib (AZD6244)(ARRY-142886) in Combination With Irinotecan in Previously Treated Patients With ColorecThe purpose of this study is to determine whether treatment with Selumetinib (AZD6244) (Hyd-Sulfate) in combination with Irinotecan as a second treatment in patients with K-ras or…NCT01116271·Los Angeles, California and 11 others

CompletedTPST-1120 as Monotherapy and in Combination With Nivolumab in Subjects With Advanced CancersThis is a phase 1/1b open label, multicenter dose escalation and dose expansion study to investigate the safety, tolerability and anti-tumor activity of TPST-1120, a small…NCT03829436·San Francisco, California and 10 others

TerminatedPhase 2a Study of BAX69 and 5-FU/Leucovorin or Panitumumab Versus Standard of Care in Subjects With Metastatic Colorectal CancerThe purpose of this study is to evaluate the safety and tolerability of BAX69 in combination with 5-fluorouracil (5-FU)/leucovorin (LV) or panitumumab to determine the recommended…NCT02448810·Port Saint Lucie, Florida and 11 others

Active not recruitingPhase 1/2 Study of MRTX849 in Patients With Cancer Having a KRAS G12C Mutation KRYSTAL-1This study will evaluate the safety, tolerability, drug levels, molecular effects, and clinical activity of MRTX849 (adagrasib) in patients with advanced solid tumors that have a…NCT03785249·Birmingham, Alabama and 221 others

UnknownComparison of Three Chemotherapy Regimens in Treating Patients With Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00008281·Huntsville, Alabama and 133 others

CompletedGenetic Study of Young Patients With Colorectal CancerRATIONALE: Identifying gene mutations (microsatellite instability) may allow doctors to plan effective treatment for patients who develop colorectal cancer at an early age.NCT00044967·Mobile, Alabama and 72 others

CompletedFR901228 in Treating Patients With Previously Treated Unresectable Locally Advanced or Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy, such as FR901228, work in different ways to stop tumor cells from dividing so they stop growing or die.NCT00077337·Mobile, Alabama and 87 others

TerminatedA Study of BDTX-189, an Orally Available Allosteric ErbB Inhibitor, in Patients With Advanced Solid Tumors.This was a clinical study with an orally administered drug, BDTX-189 in participants with advanced solid tumors that had select mutations or alterations in human epidermal growth…NCT04209465·Scottsdale, Arizona and 37 others

TerminatedA Study of ABT-165 Plus FOLFIRI vs Bevacizumab Plus FOLFIRI in Subjects With Metastatic Colorectal Cancer Previously Treated With Fluoropyrimidine, Oxaliplatin and BevacizumabA study to evaluate the efficacy and tolerability of ABT-165 plus FOLFIRI compared to bevacizumab plus FOLFIRI in participants with previously treated metastatic adenocarcinoma of…NCT03368859·Chandler, Arizona and 64 others

CompletedLYT-200 Alone and in Combination With Chemotherapy or Tislelizumab in Patients With Locally Advanced or Metastatic Solid TumorsA Phase 1/2 Open-label, Multi-center Study of the Safety, Pharmacokinetics, and Anti-tumor Activity of LYT-200 Alone and in Combination with Chemotherapy or Tislelizumab in…NCT04666688·Los Angeles, California and 11 others

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