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Clareo Health | Colorectal Cancer Clinical Trials in Boston | 363 Studies

Clinical Trials Colorectal CancerBoston

Colorectal Cancer Clinical Trials in Boston

Find 363 clinical trials for colorectal cancer near Boston, Massachusetts. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Boston

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 181-200 of 363 trials

CompletedSafety and Efficacy Study of AMG 820 and Pembrolizumab Combination in Select Advanced Solid Tumor CancerA multi-center Phase 1b/2 study testing the combination of AMG 820 and pembrolizumab in subjects with select advanced solid tumors.NCT02713529·Atlanta, Georgia and 14 others CompletedStudy of Encorafenib + Cetuximab Plus or Minus Binimetinib vs. Irinotecan/Cetuximab or Infusional 5-Fluorouracil (5-FU)/Folinic Acid (FA)/Irinotecan (FOLFIRI)/Cetuximab With a Safety Lead-in of Encorafenib + Binimetinib + Cetuximab in Patients With BRAF V600E-mutant Metastatic Colorectal CancerThis is a multicenter, randomized, open-label, 3-arm Phase 3 study to evaluate encorafenib + cetuximab plus or minus binimetinib versus Investigator's choice of either…NCT02928224·Phoenix, Arizona and 417 others

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Data from ClinicalTrials.govTerms

TerminatedA Study of mRNA-5671/V941 as Monotherapy and in Combination With Pembrolizumab (V941-001)This study will determine the safety and tolerability and establish a preliminary recommended Phase 2 dose of V941(mRNA-5671/V941) as a monotherapy and in combination with…NCT03948763·Gilbert, Arizona and 25 others

CompletedPaired Promotion of Colorectal Cancer and Social Determinants of Health ScreeningThis work is an implementation science study that examines different aspects of implementing a single intervention.NCT04585919·Boston, Massachusetts and 3 others

RecruitingFOG-001 in Locally Advanced or Metastatic Solid TumorsThe goal of this clinical trial is to determine if FOG-001 is safe and effective in participants with locally advanced or metastatic solid tumors or in participants with familial…NCT05919264·Phoenix, Arizona and 32 others

TerminatedStudy of Intratumorally Administered Stimulator of Interferon Genes (STING) Agonist E7766 in Participants With Advanced Solid Tumors or Lymphomas - INSTAL-101This is an open label, multicenter, phase 1/1b study to assess safety/tolerability and preliminary clinical activity of E7766 as a single agent administered intratumorally in…NCT04144140·New Haven, Connecticut and 12 others

TerminatedStudy of Imprime PGG® in Combination With Cetuximab in Subjects With Recurrent or Progressive KRAS Wild Type Colorectal CancerStudy BT-CL-PGG-CRC1031 is a Phase 3, open-label, randomized, multi-center study.NCT01309126·Florence, Alabama and 52 others

CompletedCapecitabine and Oxaliplatin or Standard Follow-Up Care in Treating Patients Who Have Undergone Surgery for Locally Advanced Rectal CancerRATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT00427713·Ashington, England and 71 others

CompletedA Dose Escalation and Cohort Expansion Study of NKTR-214 in Combination With Nivolumab and Other Anti-Cancer Therapies in Patients With Select Advanced Solid TumorsIn this four-part study, NKTR-214 was administered in combination with nivolumab and with/without other anticancer therapies.NCT02983045·La Jolla, California and 57 others

CompletedInvestigating Cabozantinib in Patients With Refractory Metastatic Colorectal CancerThis study seeks to use Cabozantinib to treat those with Metastatic Colorectal Cancer who have not previously responded to treatment.NCT03542877·Tucson, Arizona and 9 others

RecruitingBeamion BCGC-1: A Study to Find a Suitable Dose of Zongertinib Used Alone and in Combination With Other Treatments to Test Whether it Helps People With Different Types of HER2+ Cancer That Has SpreadThis study is open to adults aged 18 years and older with different types of HER2+ cancer that has spread and cannot be removed by surgery.NCT06324357·Cerritos, California and 103 others

Not yet recruitingIKS04 Regimen in Advanced Solid Tumors That Express CA242This study will evaluate the safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of the IKS04 Regimen and identify a recommended phase…NCT07738939·Los Angeles, California and 3 others

TerminatedCediranib Maleate and Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung CancerThis phase I trial is studying the side effects and best dose of cediranib maleate when given together with whole brain radiation therapy in treating patients with brain…NCT00937482·Boston, Massachusetts

CompletedTemsirolimus (CCI-770, Torisel) Combined With Cetuximab in Cetuximab-Refractory Colorectal CancerIn this study, the investigational drug, temsirolimus, will be combined with cetuximab, a biologic agent used in the treatment of colorectal cancer.NCT00593060·Boston, Massachusetts and 1 other

CompletedClinical Validation of An Optimized Multi-Target Stool DNA (Mt-sDNA 2.0) Test, for Colorectal Cancer Screening "BLUE-C"The primary objective of this study is to assess the sensitivity for colorectal cancer (CRC) and specificity of the mt-sDNA 2.0 test.NCT04144738·Birmingham, Alabama and 194 others

CompletedComputerized and Mailed Reminders in Increasing the Rate of Colorectal Cancer Screening in Adults With an Average Risk for Colorectal CancerRATIONALE: Screening may help doctors find colorectal cancer sooner, when it may be easier to treat.NCT00355004·Boston, Massachusetts and 2 others

RecruitingClonal Hematopoiesis Chemotherapy and Radiation Effects StudyThe goal of the Clonal Hematopoiesis Chemotherapy and Radiation Effects (CH CARE) Study is to understand how the presence or absence of clonal hematopoiesis (CH) influences…NCT07675967·Boston, Massachusetts

CompletedA Safety Study of MM-121 With Cetuximab and Irinotecan in Patients With Advanced CancersThe purpose of this study was to evaluate the safety and tolerability of escalating doses of the MM-121 plus cetuximab and the MM-121 plus cetuximab plus irinotecan combination.NCT01451632·San Francisco, California and 3 others

CompletedStudy of LGX818 and Cetuximab or LGX818, BYL719, and Cetuximab in BRAF Mutant Metastatic Colorectal CancerThis study will assess the safety and efficacy of LGX818 when combined with cetuximab or combined with cetuximab and BYL719 in patients with BRAF mutant metastatic colorectal…NCT01719380·Los Angeles, California and 51 others

Not yet recruitingA Study of Olomorasib (LY3537982) in Participants With Advanced Colorectal Cancer and a KRAS G12C MutationThe main purpose of this study is to evaluate how well olomorasib is tolerated and what side effects may occur when combined with other interventions in participants with Kirsten…NCT07814417·Birmingham, Alabama and 17 others

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