Breast Cancer Clinical Trials

Showing 741-760 of 5,597 trials

Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore

NCT07116161

The purpose of this research study is to investigate the acceptability, feasibility, and effectiveness of exercise therapy and cognitive behavioral therapy (CBT) in improving fatigue levels and breast cancer treatment adherence in breast cancer patients.

FatigueBreast Cancer Female

National Cancer Centre, Singapore100 participantsStarted Jul 2025

Singapore, Singapore • Singapore, Singapore • Singapore, Singapore +1 more locations

Active Not RecruitingPhase 2

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

NCT06001762

In this research study, investigators are testing if a dose-increasing strategy for abemaciclib will have less side effects and be better tolerated than the standard dosage of abemaciclib for participants with early-stage high-risk hormone receptor positive breast cancer. The names of the study drugs involved in this study are: * Abemaciclib (CDK4 and CDK6 inhibitor) * Tamoxifen (Selective estrogen receptor modulator) * Anastrozole/Letrozole (Non-steroidal aromatase inhibitors) * Exemestane (steroidal aromatase inhibitor) * LHRH (Gonadotropin-releasing hormone agonist, or Luteinizing hormone-releasing hormone agonist)

Breast CancerEarly-stage Breast CancerHigh Risk Breast Carcinoma

Dana-Farber Cancer Institute90 participantsStarted Oct 2023

Stamford, Connecticut, United States • Brewer, Maine, United States • Scarborough, Maine, United States +9 more locations

Exercise Therapy and Cognitive Behavioural Therapy for Fatigue in Female Cancer Patients in Singapore

TRADE: Dose Escalation Tolerability of Abemaciclib in HR+ HER2- Early Stage Breast Cancer

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