Known CNS disease including, but not limited to, metastases

History of exposure to certain cumulative doses of anthracyclines

Grade 3 or higher hypersensitivity reaction to prior receipt of any antibody therapy

Active and clinically significant bacterial, fungal, or viral infection

Abnormal cardiac function defined by a LVEF \<50% by ECHO or MUGA

Patients with previous history or active interstitial lung disease or pulmonary fibrosis, or a history of other clinically significant lung diseases

PF-06804103 Dose Escalation in HER2 Positive and Negative (Negative Only in Part 2) Solid Tumors