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Clareo Health | Breast Cancer Clinical Trials in Tennessee | 991 Studies

Clinical Trials Breast CancerTennessee

Breast Cancer Clinical Trials in Tennessee

Find 991 clinical trials for breast cancer near Tennessee. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Tennessee

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 121-140 of 991 trials

RecruitingS1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac ToxicityThis trial has two cohorts of patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body.NCT03418961·Anchorage, Alaska and 589 others

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Data from ClinicalTrials.govTerms

Active not recruitingT-DM1 and Tucatinib Compared With T-DM1 Alone in Preventing Relapses in People With High Risk HER2-Positive Breast Cancer, the CompassHER2 RD TrialThis phase III trial compares the effect of usual treatment with trastuzumab emtansine (T-DM1) alone vs. T-DM1 in combination with tucatinib.NCT04457596·Birmingham, Alabama and 1175 others

RecruitingT-DXd Based Therapy Followed by Endocrine Therapy Plus Dual HER2 Blockade in First-line HER2+/ HR+ Metastatic Breast Cancer and Retreatment With T-DXdThis study will evaluate a structured sequential treatment strategy starting with T-DXd + pertuzumab upfront therapy, followed by an optimized maintenance therapy with dual…NCT07683754·Columbia, Maryland and 4 others

CompletedA Trial of Paclitaxel and Bevacizumab vs. Gemcitabine, Paclitaxel, and Bevacizumab in Advanced Breast CancerThis study will compare the cancer response to both treatments for locally advanced or metastatic breast cancerNCT00320541·Fayetteville, Arkansas and 31 others

Active not recruitingSafety and Efficacy Study of the Xoft® Axxent® eBx® IORT System®The purpose of this trial is to assess the safety and efficacy of the Xoft Axxent eBx System when used for single-fraction IORT in early stage breast cancer.NCT01644669·Tucson, Arizona and 23 others

TerminatedCabazitaxel Plus Lapatinib as Therapy for HER2-Positive Metastatic Breast Cancer Patients With Intracranial MetastasesThis phase II trial will combine two agents, cabazitaxel and lapatinib, to treat patients with metastatic breast cancer (MBC) which has metastasized to the brain.NCT01934894·Fort Myers, Florida and 3 others

CompletedA Dose Finding Study of ZW49 in Patients With HER2-Positive CancersThis is a first-in-human, Phase 1, multicenter, open-label, dose-escalation study to establish the maximum-tolerated dose (MTD) or recommended dosage (RD) of ZW49, the…NCT03821233·Duarte, California and 15 others

CompletedThe STRIVE Study: Development of a Blood Test for Early Detection of Multiple Cancer TypesGRAIL is using high-intensity sequencing of circulating cell-free nucleic acids (cfNAs) to develop blood tests to detect cancer early.NCT03085888·Phoenix, Arizona and 34 others

Active not recruitingStudy of LEE011, BYL719 and Letrozole in Advanced ER+ Breast CancerThe purpose of this trial is to inform the future clinical development of the two investigational agents in ER+ breast cancer, LEE011 (CDK4/6 inhibitor) and BYL719 (PI3K-alpha…NCT01872260·San Diego, California and 24 others

CompletedFulvestrant, Palbociclib and Erdafitinib in ER+/HER2-/FGFR-amplified Metastatic Breast CancerThis is an open-label, multi-institution, phase Ib trial that evaluates the safety and tolerability and preliminary anti-tumor activity of fulvestrant, palbociclib and erdafitinib…NCT03238196·Birmingham, Alabama and 5 others

Active not recruitingTesting Olaparib Either Alone or in Combination With Atezolizumab in BRCA Mutant Non-HER2-positive Breast CancerThis randomized phase II trial studies how well olaparib with or without atezolizumab work in treating patients with non-HER2-positive breast cancer that has spread to nearby…NCT02849496·Phoenix, Arizona and 57 others

Active not recruitingTrastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)The study will evaluate the efficacy and safety of trastuzumab deruxtecan (also known as T-DXd, DS-8201a), either alone or in combination with pertuzumab, in treating patients…NCT04784715·Tucson, Arizona and 282 others

TerminatedEvaluate BL-M17D1 in Patients w/HER2-Expressing/Mutant Advanced or Metastatic Solid TumorsThe objective of this study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of BL-M17D1 in patients with HER2-Expressing or HER2-Mutant Advanced or Metastatic…NCT06714617·Denver, Colorado and 8 others

TerminatedA Study of Ruxolitinib in Combination With Capecitabine in Subjects With Advanced or Metastatic HER2-negative Breast CancerThis was a randomized, double-blind, placebo-controlled phase 2 clinical trial comparing the overall survival of women with advanced or metastatic HER2-negative breast cancer who…NCT02120417·Birmingham, Alabama and 105 others

CompletedStudy of Chemotherapy in Combination With IDO Inhibitor in Metastatic Breast CancerThe purpose of this study is to compare the effects, good and/or bad, of standard of care therapy (docetaxel or paclitaxel) with or without the addition of 1-Methyl-D-tryptophan…NCT01792050·Gainesville, Florida and 39 others

CompletedPF-3512676 (CPG 7909) Injection For Patients Who Completed An Oncology Study Using PF-3512676 (CPG 7909)This protocol allows patients who completed Coley oncology studies using PF-3512676 (CPG 7909) Injection to continue receiving the treatment until disease progression.NCT00043368·Berkely, California and 31 others

CompletedA Study of the Safety, Efficacy, and Pharmacokinetics of Tiragolumab in Combination With Atezolizumab and Chemotherapy in Participants With Triple-Negative Breast CancerThe purpose of this study is to evaluate the safety, efficacy, and pharmacokinetics of tiragolumab in combination with atezolizumab and chemotherapy in participants with…NCT04584112·Birmingham, Alabama and 23 others

Active not recruitingPhase IIIb Study of Ribociclib + ET in Early Breast CancerThe purpose of this open-label, multicenter, phase IIIb, single-arm study is to characterize the efficacy and safety of the combination of ribociclib and standard adjuvant…NCT05827081·Birmingham, Alabama and 213 others

CompletedEffect of Zoledronic Acid as Anti-Cancer Treatment in Metastatic Breast Cancer PatientsThis study will evaluate zoledronic acid's anti-cancer effects and Circulating Tumor Cell (CTCs) measurements in patients with HER2-negative metastatic breast cancer without bone…NCT01129336·Fayetteville, Arkansas and 32 others

CompletedTrial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast CancerThe primary purpose of phase 1 portion of this study is to determine the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of H3B-6545 in women with locally…NCT03250676·Goodyear, Arizona and 38 others

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