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Clareo Health | Breast Cancer Clinical Trials in Tennessee | 983 Studies

Clinical Trials Breast CancerTennessee

Breast Cancer Clinical Trials in Tennessee

Find 983 clinical trials for breast cancer near Tennessee. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 481-500 of 983 trials

RecruitingAdding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast CancerThis phase III trial compares the addition of an immunotherapy drug (durvalumab) to usual chemotherapy versus usual chemotherapy alone in treating patients with MammaPrint High 2…NCT06058377·Birmingham, Alabama and 556 others

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Data from ClinicalTrials.govTerms

TerminatedIntra-Operative Radiation Therapy Immediately Following Resection of Early Stage Breast CancerThis is a physician sponsored multi-center, non-randomized, prospectively enrolling data collection study of patients with early stage breast cancer treated with electronic…NCT02040493·Casa Grande, Arizona and 6 others

CompletedA 2-Week Ketogenic Diet in Combination With Letrozole to Modulate PI3K Signaling in ER+ Breast CancerThis is a neoadjuvant study to determine the feasibility and tolerability of 2 weeks of a very low carbohydrate ketogenic diet in combination with letrozole for patients with…NCT03962647·Nashville, Tennessee

CompletedNiraparib in Combination With Pembrolizumab in Patients With Triple-negative Breast Cancer or Ovarian CancerThis Phase 1/2 study will evaluate the safety and efficacy of combination treatment with niraparib and pembrolizumab (MK-3475) in patients with advanced or metastatic…NCT02657889·Birmingham, Alabama and 29 others

TerminatedA Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced CancersMulti-center, open-label, first in human Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous…NCT04025216·Phoenix, Arizona and 9 others

TerminatedStudy of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).This is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in…NCT03742349·New York, New York and 12 others

RecruitingNeoadjuvant Neratinib in Stage I-III HER2-Mutated Lobular Breast CancersThis phase II trial tests how well neratinib prior to the primary treatment (neoadjuvant) works in treating patients with stage I-III HER2 mutated lobular breast cancers.NCT05919108·Atlanta, Georgia and 4 others

CompletedTrial of H3B-6545, in Women With Locally Advanced or Metastatic Estrogen Receptor-positive, HER2 Negative Breast CancerThe primary purpose of phase 1 portion of this study is to determine the maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of H3B-6545 in women with locally…NCT03250676·Goodyear, Arizona and 38 others

TerminatedA Study to Evaluate the Safety and Tolerability of Venetoclax Tablets in Combination With Capecitabine Tablets in Adult Participants With Hormone Receptor-Positive, HER2-Negative Locally Advanced or Metastatic Breast Cancer Who Had Disease Progression During or After CDK4/6 Inhibitor TherapyEndocrine therapy is the initial treatment for most hormone receptor positive (HR+), human epidermal growth factor receptor 2 negative (HER2-) breast cancers.NCT04274933·Joliet, Illinois and 17 others

TerminatedStudy of Neoadjuvant Carboplatin, Eribulin and Trastuzumab for Operable HER2 Positive Breast CancerThis study will evaluate the safety and efficacy of eribulin in combination with carboplatin and trastuzumab in the neoadjuvant setting in subjects who are human epidermal growth…NCT01388647·Fort Lauderdale, Florida and 3 others

CompletedA Study of Ipatasertib in Combination With Atezolizumab and Paclitaxel as a Treatment for Participants With Locally Advanced or Metastatic Triple-Negative Breast CancerThis study evaluated the efficacy and safety of ipatasertib in combination with atezolizumab and paclitaxel in locally advanced or metastatic Triple-Negative Breast Cancer (TNBC)…NCT04177108·Mobile, Alabama and 181 others

RecruitingcfDNA Assay Prospective Observational Validation for Early Cancer Detection and Minimal Residual DiseaseThis is an observational case-control study to train and validate a genome-wide methylome enrichment platform to detect multiple cancer types and to differentiate amongst cancer…NCT05366881·Duarte, California and 16 others

RecruitingStudy of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and in Patients With Other Advanced Solid TumorsPhase I: Characterize safety and tolerability of ECI830 as a single agent and in combination with ribociclib and fulvestrant.NCT06726148·Los Angeles, California and 32 others

Active not recruitingA Study of Dato-DXd With or Without Durvalumab Versus Investigator's Choice of Therapy in Patients With Stage I-III Triple-negative Breast Cancer Without Pathological Complete Response Following Neoadjuvant Therapy (TROPION-Breast03)This is a Phase III, randomized, open-label, 3-arm, multicenter, international study assessing the efficacy and safety of Dato-DXd with or without durvalumab compared with ICT in…NCT05629585·Gilbert, Arizona and 275 others

CompletedStudy of the Safety and Pharmacology of GDC-0980 in Combination With Paclitaxel With or Without Bevacizumab in Patients With Locally Recurrent or Metastatic Breast CancerThis is an open-label, multicenter, Phase Ib dose-escalation study to assess the safety, tolerability, and pharmacokinetics of GDC-0980 administered with taxane-based chemotherapy…NCT01254526·Boston, Massachusetts and 2 others

CompletedStudy of Sacituzumab Govitecan-hziy (IMMU-132) in Adults With Epithelial CancerThe primary objective in Phase I is to evaluate the safety and tolerability of sacituzumab govitecan-hziy (SG) as a single agent administered in 21-day treatment cycles in…NCT01631552·Aurora, Colorado and 11 others

CompletedA Study of Single-Agent Eribulin Mesylate as First-Line Therapy for Locally Recurrent or Metastatic Human Epidermal Growth Factor Receptor Two (HER2) Negative Breast CancerThe purpose of this study is to assess the efficacy and safety of single-agent eribulin mesylate for first-line treatment of subjects with locally recurrent or metastatic breast…NCT01268150·Miami, Florida and 16 others

Active not recruitingTesting MK-3475 (Pembrolizumab) as Adjuvant Therapy for Triple Receptor-Negative Breast CancerThis randomized phase III trial studies how well pembrolizumab works in treating patients with triple-negative breast cancer.NCT02954874·Birmingham, Alabama and 918 others

TerminatedStudy Evaluating CCI-779 and Letrozole in Post-menopausal Women With Breast CancerIn this clinical research study, postmenopausal subjects with metastatic breast cancer will be given either the combination of temsirolimus (CCI-779) and letrozole or a placebo…NCT00083993·Hoover, Alabama and 128 others

CompletedStudy of LEE011 With Fulvestrant and BYL719 or BKM120 in Advanced Breast CancerThe purpose of this trial is to explore the clinical utility of the three investigational agents in HR+, HER2- breast cancer.NCT02088684·Birmingham, Alabama and 10 others

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