Breast Cancer Clinical Trials in Pennsylvania

Showing 261-280 of 353 trials

Effect of Pharmacogenomics Differences in Phase I and II Metabolism of Tamoxifen on Efficacy and Toxicity

NCT00886535

This study will be an open-label prospective observational trial designed to test associations between polymorphisms of candidate genes and tamoxifen. Pre- and post-menopausal women taking tamoxifen as standard therapy or chemopreventive therapy will be included in this study.

Breast CancerDuctal Carcinoma in Situ

Milton S. Hershey Medical Center41 participantsStarted Feb 2010

Hershey, Pennsylvania, United States

COMPLETEDPHASE240 miles

Combination Chemotherapy and Trastuzumab in Treating Women With Metastatic Breast Cancer

NCT00003612

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. PURPOSE: Phase II trial to study the effectiveness of combining paclitaxel, carboplatin, and trastuzumab in treating women who have metastatic breast cancer that overexpresses HER2.

Breast Cancer

Alliance for Clinical Trials in Oncology92 participantsStarted Apr 1999

Scottsdale, Arizona, United States • Jacksonville, Florida, United States • Peoria, Illinois, United States +22 more locations

Effect of Pharmacogenomics Differences in Phase I and II Metabolism of Tamoxifen on Efficacy and Toxicity

Combination Chemotherapy and Trastuzumab in Treating Women With Metastatic Breast Cancer

Breast Cancer Trials in Other Cities

Study Evaluating The Combination Of Neratinib And Capecitabine In Solid Tumors And Breast Cancer

Lapatinib and Trastuzumab With or Without Endocrine Therapy

MRI to Detect Breast Tumors in Women

Magnetic Resonance Imaging in Women Recently Diagnosed With Unilateral Breast Cancer

Evaluate Risk/Benefit of Nab Paclitaxel in Combination With Gemcitabine and Carboplatin Compared to Gemcitabine and Carboplatin in Triple Negative Metastatic Breast Cancer (or Metastatic Triple Negative Breast Cancer)

A Phase III Study of BKM120 With Fulvestrant in Patients With HR+,HER2-, AI Treated, Locally Advanced or Metastatic Breast Cancer Who Progressed on or After mTORi

A Study of Abemaciclib (LY2835219) in Participants With HR+, HER2- Advanced Breast Cancer

CYP17 Lyase and Androgen Receptor Inhibitor Treatment With Seviteronel Trial (INO-VT-464-006; NCT02580448)

Study Evaluating Neratinib (HKI-272) In Combination With Vinorelbine In Subjects With Solid Tumors And Metastatic Breast Cancer

Study of Albumin-bound Paclitaxel (Abraxane) in Combination With Carboplatin and Herceptin in Patients With Advanced Breast Cancer

Nueva Vida Intervention for Latina Breast Cancer Survivors and Caregivers

Assessment of Diagnostic Accuracy and Performance of Digital Breast Tomosynthesis Compared to Mammography (ADAPT)

A Multi-Center Study of Ibrutinib in Combination With MEDI4736 in Subjects With Relapsed or Refractory Solid Tumors

Safety Study of Enzalutamide (MDV3100) in Patients With Incurable Breast Cancer

AirXpanders AeroForm Tissue Expander System for Breast Reconstruction

A Study of SC-005 in Subjects With Triple Negative Breast Cancer (TNBC)

A Study of a Combination of Trastuzumab and Capecitabine With or Without Pertuzumab in Patients With HER2-positive Metastatic Breast Cancer (PHEREXA)

Open Label, Multi-center Study to Assess the Safety, Tolerability and Pharmacokinetics of CUDC-907 in Subjects With Advanced/Relapsed Solid Tumors

Other Conditions in Pennsylvania