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Clareo Health | Breast Cancer Clinical Trials in Cleveland | 440 Studies

Clinical Trials Breast CancerCleveland

Breast Cancer Clinical Trials in Cleveland

Find 440 clinical trials for breast cancer near Cleveland, Ohio. Connect with research centers in your area.

All Breast Cancer trials nationwide All trials in Cleveland

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 61-80 of 440 trials

Active not recruitingStudy BT8009-100 in Subjects With Nectin-4 Expressing Advanced MalignanciesThis study is a Phase I/II, multicenter, first-in-human, open-label dose-escalation study of BT8009 given as a single agent and in combination with pembrolizumab in participants…NCT04561362·Denver, Colorado and 23 others Active not recruitingExemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or MetastaticThis randomized phase III trial studies exemestane and entinostat to see how well they work compared to exemestane alone in treating patients with hormone receptor-positive breast…NCT02115282·Birmingham, Alabama and 652 others

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Data from ClinicalTrials.govTerms

CompletedT-DM1 and Palbociclib for Metastatic HER2 Breast CancerThis is a single arm, phase II study to evaluate if the combination of T-DM1 with palbociclib improves progression-free survival in patients with metastatic HER2 positive breast…NCT03530696·Tucson, Arizona and 15 others

CompletedCombination Chemotherapy in Treating Women With Breast CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00003519·Birmingham, Alabama and 133 others

CompletedType I-Polarized Autologous Dendritic Cell Vaccine With Tumor Blood Vessel Antigen-Derived Peptides in Metastatic Breast Cancer PatientsThis pilot clinical trial studies the safety of a dendritic cell vaccine when given with gemcitabine hydrochloride in treating patients with breast cancer that has spread beyond…NCT02479230·Cleveland, Ohio and 1 other

CompletedStudy Evaluating Neratinib Versus Lapatinib Plus Capecitabine For ErbB2 Positive Advanced Breast CancerThis is a study of an experimental drug (neratinib) versus a combination of drugs (lapatinib and capecitabine) in women who have erbB-2 (HER-2) positive metastatic or locally…NCT00777101·Tucson, Arizona and 151 others

RecruitingStudy of the Bria-IMT Regimen and CPI vs Physicians' Choice in Advanced Metastatic Breast Cancer.This is a multicenter randomized, open label study to evaluate overall survival with the Bria-IMT regimen in combination with Checkpoint Inhibitor \[Retifanlimab\], versus…NCT06072612·Phoenix, Arizona and 78 others

CompletedCombination of Oral WX-671 Plus Capecitabine vs. Capecitabine Monotherapy in First-line Her2-negative Metastatic Breast CancerThis randomized, double-blind, placebo controlled phase II trial is studying how well capecitabine works when given in combination with WX-671 or when given alone in treating…NCT00615940·New York, New York and 19 others

CompletedAssessment of Candidate Protein Expression in Breast Cancer SpecimensRATIONALE: Studying the genes expressed in samples of tumor tissue from patients with cancer may help doctors identify biomarkers related to cancer.NCT00918892·Cleveland, Ohio

CompletedStudy of Glembatumumab Vedotin (CDX-011) in Patients With Metastatic, gpNMB Over-Expressing, Triple Negative Breast CancerThe main purpose of this study is to see whether CDX-011 (glembatumumab vedotin, an antibody-drug conjugate) is effective in treating patients who have advanced Triple-Negative…NCT01997333·Birmingham, Alabama and 139 others

RecruitingA Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast CancerThe purpose of this study is to assess the safety of GDC-4198 alone and in combination with giredestrant and also the efficacy of GDC-4198 + giredestrant versus abemaciclib +…NCT07100106·Huntsville, Alabama and 76 others

TerminatedA Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast CancerA phase 1 study of 68Ga-R11228 and 177Lu-R11228 in breast cancer.NCT07121244·Indianapolis, Indiana and 6 others

CompletedNaF PET/MRI Evaluation for Bone Metastases in Breast CancerThis study will look at two new technologies being developed for measuring cancer in bones. One of these technologies is a substance called Sodium Fluoride (NaF).NCT02103634·Cleveland, Ohio

CompletedAssessing the Accuracy of Tumor Biopsies After Chemotherapy to Determine if Patients Can Avoid Breast SurgeryThis phase II trial studies how well biopsy of breast after chemotherapy works in predicting pathologic response in patients with stage II-IIIA breast cancer undergoing breast…NCT03188393·Birmingham, Alabama and 380 others

CompletedAdjuvant Therapy With an Alpha-lactalbumin Vaccine in Triple-Negative Breast CancerThe purpose of this study is to determine the safety as well as the most effective dose of the alpha-lactalbumin vaccine (aLA breast cancer vaccine) to treat patients with…NCT04674306·Cleveland, Ohio

CompletedRadiation Therapy in Treating Women With Stage I or Stage II Breast CancerRATIONALE: Radiation therapy may kill any tumor cells remaining after surgery.NCT00002873·Birmingham, Alabama and 231 others

CompletedRadiation Therapy After Lumpectomy in Treating Women With Ductal Carcinoma in Situ or Invasive Breast CancerRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00054301·Cleveland, Ohio

CompletedAssessment of the Efficacy and Safety of Olaparib Monotherapy Versus Physicians Choice Chemotherapy in the Treatment of Metastatic Breast Cancer Patients With Germline BRCA1/2 Mutations.This open label, randomised, controlled, multi-centre phase III study will assess the efficacy and safety of single agent olaparib vs standard of care based on physician's choice…NCT02000622·San Diego, California and 170 others

CompletedA Study of Neratinib Plus Capecitabine Versus Lapatinib Plus Capecitabine in Patients With HER2+ Metastatic Breast Cancer Who Have Received Two or More Prior HER2 Directed Regimens in the Metastatic SettingThis is a randomized, multi-center, multinational, open-label, active-controlled, parallel design study of the combination of neratinib plus capecitabine versus the combination of…NCT01808573·Chandler, Arizona and 251 others

CompletedCarboplatin, Nab-Paclitaxel and Pembrolizumab for Metastatic Triple-Negative Breast CancerThe purpose of this study is to see how effective the combination of the two chemotherapy drugs (carboplatin and nab-paclitaxel) are when added to a third drug, pembrolizumab.NCT03121352·Cleveland, Ohio and 1 other

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