Brain Cancer Clinical Trials

Showing 301-320 of 693 trials

FearLess in Cognitively Intact Patients With Glioma

NCT05604365

This study will assess the preliminary feasibility and acceptability of FearLess, a newly-developed psychological intervention for fear of cancer recurrence (FCR) among cognitively-intact patients with glioma.

GliomaFear of Cancer

Virginia Commonwealth University22 participantsStarted Nov 2022

Richmond, Virginia, United States

WITHDRAWNNA

Contribution of [18F]DPA-714 PET for Grading and Exploration of the Inflammatory Microenvironment of Glioma.

NCT05672082

The 18-kDa translocator protein (TSPO) is a mitochondrial protein that is weakly expressed in the healthy brain. However, there is an increase in the expression of TSPO in glial tumors. It is even associated with a higher malignancy and a shorter survival of patients. Among the different TSPO ligands, the most commonly used tracers in PET imaging are \[18F\]DPA-714 and 18F-GE180. We hypothesize that \[18F\]DPA-714 PET could improve the current performance for tumor grade definition in vivo, which is a major issue for the therapeutic management of gliomas.

Glioma

Center Eugene MarquisStarted Oct 2023

COMPLETEDPHASE2

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

NCT00704288

The purpose of this study is to evaluate the objective response rate and 6-month progression-free survival rate of XL184 in subjects with recurrent or progressive glioblastoma multiforme. XL184 is a new chemical entity that inhibits VEGFR2, MET and RET, kinases implicated in tumor formation, growth and migration.

Glioblastoma Multiforme

Exelixis222 participantsStarted May 2008

Los Angeles, California, United States • San Francisco, California, United States • Boston, Massachusetts, United States +5 more locations

FearLess in Cognitively Intact Patients With Glioma

Contribution of [18F]DPA-714 PET for Grading and Exploration of the Inflammatory Microenvironment of Glioma.

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

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