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Clareo Health | Brain Cancer Clinical Trials in Pennsylvania | 171 Studies

Clinical Trials Brain CancerPennsylvania

Brain Cancer Clinical Trials in Pennsylvania

Find 171 clinical trials for brain cancer near Pennsylvania. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Pennsylvania

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 121-140 of 171 trials

CompletedAdult Study: ABT-414 Alone or ABT-414 Plus Temozolomide vs. Lomustine or Temozolomide for Recurrent Glioblastoma Pediatric Study: Evaluation of ABT-414 in Children With High Grade GliomasThis study was conducted to evaluate the efficacy and safety of depatuxizumab mafodotin (ABT-414) alone or with temozolomide versus temozolomide or lomustine alone in adult…NCT02343406·Palo Alto, California and 101 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine GliomaPatients will receive a vaccine called SurVaxM on this study. While vaccines are usually thought of as ways to prevent diseases, vaccines can also be used to treat cancer.NCT04978727·Los Angeles, California and 13 others

CompletedClinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade GliomaThis is a 2 strata pilot trial within the Pacific Pediatric Neuro-Oncology Consortium (PNOC).NCT03739372·San Diego, California and 11 others

CompletedTesting Ramipril to Prevent Memory Loss in People With GlioblastomaThis study is to determine if an oral drug called Ramipril can lower the chance of memory loss in patients with glioblastoma getting chemoradiation.NCT03475186·Anchorage, Alaska and 422 others

CompletedSorafenib in Treating Patients With Recurrent or Progressive Malignant GliomaThis phase I trial is studying the side effects and best dose of sorafenib in treating patients with recurrent or progressive malignant glioma.NCT00093613·Birmingham, Alabama and 9 others

RecruitingStudy of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIThe purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) better than using…NCT07326566·Birmingham, Alabama and 31 others

Active not recruitingA Study Comparing Niraparib With Temozolomide in Adult Participants With Newly-diagnosed, MGMT Unmethylated GlioblastomaThe goal of this Phase 3 clinical trial is to compare the efficacy of niraparib versus temozolomide (TMZ) in adult participants with newly-diagnosed, MGMT unmethylated…NCT06388733·Birmingham, Alabama and 94 others

CompletedBevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent GlioblastomaThis randomized phase II trial studies how well bevacizumab with or without radiation therapy works in treating patients with recurrent glioblastoma.NCT01730950·Birmingham, Alabama and 30 others

CompletedO(6)-Benzylguanine in Treating Patients With Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00002971·Los Angeles, California and 8 others

TerminatedPost-approval Study of NovoTTF-100A in Recurrent GBM PatientsThis is a non-randomized, concurrent control study, designed to confirm that the efficacy of the NovoTTF-100A System in patients with recurrent GBM treated in a real life settings…NCT01756729·Birmingham, Alabama and 11 others

TerminatedNelfinavir Mesylate, Radiation Therapy, and Temozolomide in Treating Patients With Glioblastoma MultiformeRATIONALE: Nelfinavir mesylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00915694·Philadelphia, Pennsylvania

WithdrawnStudy of Therapy With TransMID™ Compared to Best Standard of Care in Patients With Glioblastoma MultiformeTransMID treatment or best standard of care for patients with advanced glioblastoma multiforme Glioblastoma multiforme (GBM) is a type of brain tumour.NCT00083447·La Jolla, California and 24 others

RecruitingSonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBMThe brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls.NCT05902169·Phoenix, Arizona and 55 others

TerminatedMK0752 in Treating Young Patients With Recurrent or Refractory CNS CancerRATIONALE: MK0752 may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00572182·San Francisco, California and 11 others

CompletedGene Therapy in Treating Patients With Recurrent Malignant GliomasRATIONALE: Inserting the gene for adenovirus p53 into a person's tumor may improve the body's ability to fight cancer.NCT00004041·San Francisco, California and 7 others

WithdrawnMultimodality MRI and Liquid Biopsy in GBMPatients with a new diagnosis of high-grade glioma based on MRI, who are considered surgical candidates determined by neurosurgeons or patients with recurrent glioblastoma with…NCT04776980·Philadelphia, Pennsylvania

CompletedBevacizumab With or Without Trebananib in Treating Patients With Recurrent Brain TumorsThis partially randomized phase II trial with a safety run-in component studies the side effects and how well bevacizumab given with or without trebananib works in treating…NCT01609790·Anchorage, Alaska and 243 others

CompletedDose Confirmation Study of Cotara for the Treatment of Glioblastoma Multiforme at First RelapseCotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody.NCT00677716·Phoenix, Arizona and 6 others

CompletedPenicillamine, Low Copper Diet, and Radiation Therapy in Treating Patients With GlioblastomaRATIONALE: Penicillamine may stop the growth of glioblastomas by stopping blood flow to the tumor. A diet low in copper may interfere with the growth of brain tumor cells.NCT00003751·Birmingham, Alabama and 8 others

TerminatedAXL Inhibitor BGB324 in Treating Participants With Recurrent Glioblastoma Undergoing SurgeryThis phase I trial studies how well AXL inhibitor BGB324 works in treating participants with glioblastoma that has come back who are undergoing surgery.NCT03965494·Birmingham, Alabama and 5 others

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