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Clareo Health | Brain Cancer Clinical Trials in Pennsylvania | 171 Studies

Clinical Trials Brain CancerPennsylvania

Brain Cancer Clinical Trials in Pennsylvania

Find 171 clinical trials for brain cancer near Pennsylvania. Connect with research centers in your area.

All Brain Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 41-60 of 171 trials

CompletedChemotherapy in Treating Patients With Progressive or Recurrent Brain TumorsRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00012038·Birmingham, Alabama and 9 others RecruitingTesting the Addition of an Anti-cancer Drug, Selinexor, to the Usual Chemotherapy Treatment (Temozolomide) for Brain Tumors That Have Returned After Previous TreatmentThis phase I/II trial tests the safety, side effects and best dose of selinexor given in combination with the usual chemotherapy (temozolomide) and compares the effect of this…NCT05432804·Phoenix, Arizona and 35 others

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Data from ClinicalTrials.govTerms

CompletedA Study of Abemaciclib (LY2835219) in Combination With Other Anti-Cancer Treatments in Children and Young Adult Participants With Solid Tumors, Including NeuroblastomaThe study's purpose is to see if the drug, abemaciclib, is safe and effective when given with other drugs to kill cancer cells.NCT04238819·Phoenix, Arizona and 24 others

CompletedAnti-LAG-3 Alone & in Combination w/ Nivolumab Treating Patients w/ Recurrent GBM (Anti-CD137 Arm Closed 10/16/18)This phase I trial studies the safety and best dose of anti-LAG-3 (anti-LAG-3 monoclonal antibody BMS-986016) or urelumab alone and in combination with nivolumab in treating…NCT02658981·Birmingham, Alabama and 10 others

CompletedSurgery Followed by Radiation Therapy in Treating Patients With Newly Diagnosed Glioblastoma MultiformeRATIONALE: Internal radiation uses radioactive material placed directly into or near a tumor to kill tumor cells.NCT00053183·Birmingham, Alabama and 9 others

RecruitingSonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBMThe brain is protected from any toxic or inflammatory molecule by the blood-brain barrier (BBB). This physical barrier is located at the level of the blood vessel walls.NCT05902169·Phoenix, Arizona and 55 others

CompletedSorafenib in Treating Patients With Recurrent or Progressive Malignant GliomaThis phase I trial is studying the side effects and best dose of sorafenib in treating patients with recurrent or progressive malignant glioma.NCT00093613·Birmingham, Alabama and 9 others

CompletedCyproheptadine and Megestrol in Preventing Weight Loss in Children With Cachexia Caused By Cancer or Cancer TreatmentRATIONALE: Cyproheptadine and megestrol may improve appetite and help prevent weight loss in children with cancer.NCT00066248·Oakland, California and 42 others

CompletedThe PRECISE Trial: Study of IL13-PE38QQR Compared to GLIADEL Wafer in Patients With Recurrent Glioblastoma MultiformeThe purpose of the PRECISE trial is to determine whether overall survival duration, safety, and quality of life are improved for patients treated with IL13-PE38QQR compared to…NCT00076986·Birmingham, Alabama and 59 others

RecruitingStudy of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIIIThe purpose of this study is to see if combining silevertinib with temozolomide after surgery and radiotherapy helps treat newly diagnosed glioblastoma (GBM) better than using…NCT07326566·Birmingham, Alabama and 31 others

CompletedA Study of DSP-7888 Dosing Emulsion in Combination With Bevacizumab in Patients With Recurrent or Progressive Glioblastoma Following Initial TherapyThis is an event driven, adaptive design, a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 3 study of DSP-7888 Dosing Emulsion plus Bevacizumab…NCT03149003·Birmingham, Alabama and 60 others

TerminatedCelecoxib in Patients With Newly Diagnosed GBM Who Are Receiving Anticonvulsant Drugs and Undergoing RTRATIONALE: Celecoxib may stop the growth of tumor cells by blocking the enzymes necessary for their growth.NCT00068770·Tampa, Florida and 6 others

CompletedGefitinib Plus Temozolomide in Treating Patients With Malignant Primary GliomaRATIONALE: Biological therapies such as gefitinib may interfere with the growth of cancer cells and slow the growth of the tumor.NCT00027625·Los Angeles, California and 10 others

CompletedSafety & Radiation Distribution Study of Cotara® in Patients With Recurrent Glioblastoma MultiformeRATIONALE: Cotara® is an experimental new treatment that links a radioactive isotope (iodine 131) to a targeted monoclonal antibody.NCT00509301·Phoenix, Arizona and 3 others

CompletedTipifarnib in Treating Patients With Recurrent or Progressive Malignant GliomaRATIONALE: Tipifarnib may stop the growth of tumor cells by blocking the enzymes necessary for tumor cell growth.NCT00005859·Los Angeles, California and 10 others

CompletedRamucirumab or Anti-PDGFR Alpha Monoclonal Antibody IMC-3G3 in Treating Patients With Recurrent Glioblastoma MultiformeRATIONALE: Monoclonal antibodies, such as ramucirumab and anti-PDGFR alpha monoclonal antibody IMC-3G3 (Olaratumab), can block tumor growth in different ways.NCT00895180·Birmingham, Alabama and 10 others

Active not recruitingFimepinostat in Treating Brain Tumors in Children and Young AdultsThis trial studies how well fimepinostat works in treating patients with newly diagnosed diffuse intrinsic pontine glioma, or medulloblastoma, or high-grade glioma that have come…NCT03893487·Los Angeles, California and 18 others

TerminatedGamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Recurrent or Progressive GlioblastomaThis phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with recurrent or progressive glioblastoma.NCT01122901·Atlanta, Georgia and 4 others

CompletedSafety Study of Aminolevulinic Acid (ALA) to Improve Visibility of Brain Tumors During SurgeryA one time oral dose of ALA is taken before surgery.NCT00961090·Pittsburgh, Pennsylvania

CompletedO6-Benzylguanine and Carmustine Implants in Treating Patients With Recurrent Malignant GliomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00004892·Birmingham, Alabama and 8 others

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