Brain Cancer Clinical Trials in North Carolina

Showing 21-40 of 93 trials

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

NCT02101905

This pilot phase I clinical trial studies how well lapatinib ditosylate before surgery works in treating patients with high-grade glioma that has come back after a period of time during which the tumor could not be detected. Lapatinib ditosylate may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Anaplastic AstrocytomaAnaplastic EpendymomaAnaplastic Oligodendroglioma+4 more

National Cancer Institute (NCI)29 participantsStarted Nov 2016

Los Angeles, California, United States • Baltimore, Maryland, United States • Boston, Massachusetts, United States +9 more locations

TERMINATEDPHASE141 miles

Feasibility Study on LITT for Newly Diagnosed Glioblastoma

NCT02880410

Multicenter, open-label, prospective designed study to characterize the performance of brain laser interstitial thermal therapy (LITT) ablation using the Monteris NeuroBlate System in combination with standard of care radiation therapy and temozolomide for the treatment of newly diagnosed glioblastomas (GBM).

Glioblastoma

Monteris Medical3 participantsStarted Aug 2017

St Louis, Missouri, United States • Winston-Salem, North Carolina, United States • Cleveland, Ohio, United States +1 more locations

Lapatinib Ditosylate Before Surgery in Treating Patients With Recurrent High-Grade Glioma

Feasibility Study on LITT for Newly Diagnosed Glioblastoma

Brain Cancer Trials in Other Cities

Study of IDO Inhibitor and Temozolomide for Adult Patients With Primary Malignant Brain Tumors

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

9-ING-41 in Pediatric Patients With Refractory Malignancies.

Study of XL184 (Cabozantinib) in Adults With Glioblastoma Multiforme

Laser Ablation in Stereotactic Neurosurgery (LAISE): NeuroBlate® Retrospective Registry

89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors

Study of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Testing the Addition of the Immune Therapy Drugs, Tocilizumab and Atezolizumab, to Radiation Therapy for Recurrent Glioblastoma

INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)

Intermediate-size Expanded Access to ONC201 for Patients With H3 K27M-mutant and/or Midline Gliomas

Vemurafenib in Children With Recurrent/Refractory BRAF Gene V600E (BRAFV600E)-Mutant Gliomas

REGN2810 in Pediatric Patients With Relapsed, Refractory Solid, or Central Nervous System (CNS) Tumors and Safety and Efficacy of REGN2810 in Combination With Radiotherapy in Pediatric Patients With Newly Diagnosed or Recurrent Glioma

A Phase III Trial of With Marizomib in Patients With Newly Diagnosed Glioblastoma

Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma

Maximum Tolerated Dose, Safety, and Efficacy of Rhenium Nanoliposomes in Recurrent Glioma (ReSPECT)

CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma

A Study of Ad-RTS-hIL-12 With Veledimex in Subjects With Glioblastoma or Malignant Glioma

Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma

Other Conditions in North Carolina