Brain Cancer Clinical Trials in Denver

Showing 41-60 of 79 trials

INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme

NCT02386826

The purpose of this study is to determine whether the combination of two agents, INC280 and bevacizumab, is safe and effective when administered to patients with Glioblastoma Multiforme (GBM) who have progressed after receiving prior therapy or who have unresectable GBM.

Glioblastoma MultiformeGliosarcomaColorectal Cancer+1 more

SCRI Development Innovations, LLC65 participantsStarted Sep 2015

Denver, Colorado, United States • New Haven, Connecticut, United States • Kansas City, Missouri, United States +2 more locations

COMPLETEDPHASE1< 1 mile

Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas

NCT00031083

In this study an investigational replication-defective, recombinant adenovirus expressing the interferon-beta gene (BG00001) will be directly injected into tumors, in patients with recurrent Grade III and Grade IV Gliomas, in order to deliver the hIFN-beta gene. The purpose of the study is to evaluate the safety and any harmful effects of injection of BG00001 into brain tumors. Also, this study will help determine whether the virus carrying the beta interferon gene will enter brain tumor cells and cause the cancer cells to die. This study will require one hospital admission for the actual procedure of drug administration. All other visits will be conducted on an out-patient basis

Glioblastoma MultiformeAnaplastic AstrocytomaOligoastrocytoma, Mixed+1 more

Biogen12 participantsStarted Apr 2002

Birmingham, Alabama, United States • Tucson, Arizona, United States • Denver, Colorado, United States +2 more locations

INC280 Combined With Bevacizumab in Patients With Glioblastoma Multiforme

Dose Escalation Study to Determine the Safety of IFN-Beta Gene Transfer in the Treatment of Grade III & Grade IV Gliomas

Brain Cancer Trials in Other Cities

Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors

Expanded Access Protocol Using 131I-MIBG

Vorinostat and Radiation Therapy Followed by Maintenance Therapy With Vorinostat in Treating Younger Patients With Newly Diagnosed Diffuse Intrinsic Pontine Glioma

Study of Tesevatinib Monotherapy in Patients With Recurrent Glioblastoma

Temozolomide and Radiation Therapy With or Without Cediranib Maleate in Treating Patients With Newly Diagnosed Glioblastoma

First in Patient Study for PF-06840003 in Malignant Gliomas

Everolimus for Children With NF1 Chemotherapy-Refractory Radiographic Progressive Low Grade Gliomas

Bevacizumab With or Without Radiation Therapy in Treating Patients With Recurrent Glioblastoma

Gliogene: Brain Tumor Linkage Study

A Study Evaluating Ultratrace Iobenguane I131 in Patients With Malignant Relapsed/Refractory Pheochromocytoma/Paraganglioma

UNITE Study: Understanding New Interventions With GBM ThErapy

Convection-Enhanced Delivery (CED) of MDNA55 in Adults With Recurrent or Progressive Glioblastoma

Neural Stem Cell Based Virotherapy of Newly Diagnosed Malignant Glioma

Autologous Dendritic Cells Loaded With Autologous Tumor Associated Antigens for Treatment of Newly Diagnosed Glioblastoma

A Phase 1 Study Evaluating AMG 232 in Advanced Solid Tumors or Multiple Myeloma

Ipilimumab and/or Nivolumab in Combination With Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma or Gliosarcoma

Incidence of Intracranial Hemorrhage in Glioma Patients With Venous Thromboembolism Converted From LMWH to Apixaban

Steady State Blood Volume Maps Using Ferumoxytol Non-stoichiometric Magnetite MRI in Imaging Patients With Glioblastoma

Other Conditions in Denver