Chronic Respiratory Disease Participant Engagement Study

This study is designed for adults who have, or suspected to have, a long-term respiratory (lung) condition such as AATD, COPD, asthma, bronchiectasis, or ILD. This study will help participants become familiar with the clinical trials unit environment and research team. The findings from this study may help improve the design of future clinical trials and support the development of more patient-centred research. This is a participant engagement study and will take about 5 weeks to complete. There is no overnight stay, and no investigational drug will be given. The study involves two visits; Visit 1: An in-person engagement visit (Day 1) and Visit 2: A follow-up about 3 weeks (±14 days) after Day 1. During the Day 1 visit, participants will be asked to provide written informed consent. After providing consent, participants will be given a tour of the clinical study unit to get familiar with the environment and facilities. Following informed consent on Day 1, participants will undergo a unit tour and undergo a range of routine health assessments. These may include a review of their medical history, measurements of height, weight, blood pressure and oxygen levels, breathing tests, blood tests, heart tracing (ECG), liver assessment, and questionnaires about their symptoms and quality of life. Some participants may also undergo genetic testing if it is clinically appropriate and previous results are not available. A Follow-Up with the Study Doctor will be conducted within 3 weeks (±14 days) after Day 1 to discuss the results of the clinical assessments. The participants will have the opportunity to ask any further questions. If a participant has a confirmed new genetic or respiratory diagnosis and they are not already receiving appropriate care from a specialist, they will be provided with appropriate counselling regarding the finding and, where clinically indicated, their General Practitioner (GP) will be informed to support ongoing clinical management and will be referred to an appropriate specialist.