Inflammatory and Genetic Predictors of Cognitive and Emotional Recovery After Critical Illness

Exclusion Criteria

• •Non-authorisation by the patient and/or relatives for inclusion in the study
• •Patients admitted to a neurocritical ICU
• •History of severe neurological disease (including dementia or focal brain injury with functional and cognitive impairment) prior to ICU admission
• •History of severe psychiatric disorders (schizophrenia, bipolar disorder, major depressive disorder)
• •Intellectual disability (IQ \<80) or other neurodevelopmental disorders, such as autism spectrum disorder
• •Patients who develop secondary complications (e.g., infections, stroke, traumatic brain injury, or other non-transient acquired brain injury) after ICU discharge that may compromise the results of emotional and neuropsychological evaluations during the recovery phase
• •Moderate to severe cognitive impairment (Short-IQCODE \>57) preventing independent participation in telemedicine or face-to-face follow-up
• •Readmission to the ICU within 12 months after ICU discharge
• •Language barrier (non-Spanish- and/or non-Catalan-speaking patients)