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Studying the Impairment of Stroke and Sarcopenia Pa-tients Using Maximum Voluntary Contractions of the Leg Joints.
The goal of this study is to obtain the maximum voluntary torques of the lower-limb joints and to monitor oxygen level in the main lower-limb muscles. This will be done for three joints: i.e. the hip, knee and ankle joint and NIRS sensors will be placed on the biceps femoris, rectus femoris and gastrocnemius muscle. For the hip and knee, the maximum torque will be determined both in exertion direction and flexion direction. For the ankle, both plantarflexion and dorsiflexion will be considered. For each of these directions, the maximum joint torque will be defined for different specific joint angles and joint velocities (see procedure). For every joint and for the whole protocol for the torques measurement campaign, the different muscle of interest will be monitored with the NIRS, i.e. hip is associated with hamstring contraction, knee is associated with thigh contraction and ankle is associated with calf contraction. With these discrete points, an algorithm will be used to obtain a complete plot of the maximum torque in function of both joint angle and joint velocities. Comparing these plots between for example stroke and healthy individuals can help us understand what level of assistance stroke patients require. Comparison in oxygen level between healthy individuals and impairments population of stroke and sarcopenia patients can also help us investigate how oxygen is used depending on the population.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
Yes
Vrije Universiteit Brussel
Brussels, Belgium
Start Date
February 11, 2025
Primary Completion Date
April 1, 2026
Completion Date
February 11, 2027
Last Updated
March 11, 2026
42
ESTIMATED participants
MVC measurements of participants
OTHER
Lead Sponsor
Vrije Universiteit Brussel
NCT05093673
NCT06258538
Data Source & Attribution
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View ClinicalTrials.gov Terms and ConditionsNCT07371455