Shatavari Root Extract for Perimenopausal Symptoms

Exclusion Criteria

• •1. Participants taking any form of herbal extract in the last 3 months before study entry.
• •2. Participants who are on hormone replacement therapy (HRT) for more than 3 months.
• •3. Participants who are pregnant.
• •4. Participants with present active medical, surgical, and gynaecological problems.
• •5. Participants with a history of alcohol, tobacco dependence, or any substance abuse.
• •6. Participants who had undergone bilateral ovariectomy
• •7. Participants with history of breast or cervical carcinoma
• •8. Participants who taking medication that affect bone metabolism, including glucocorticoid, anticonvulsant, and methotrexate.
• •9. Participants with clinically relevant cardiovascular, gastrointestinal, hepatic, neurologic, endocrine, haematologic or other major systemic diseases making implementation of the protocol or other interpretation of the study result difficult.
• •10. Participants with mental condition rendering the subject unable to understand the nature, scope, and possible consequences of the study.
• •11. Participants with evidence of demonstrated inability to follow study protocols or attend follow-up visits, including poor compliance.
• •12. Participants with demonstrated inability to follow study protocols or attend follow-up visit
• •13. Participants with inability to attend follow-up visit
• •14. Participants with any other medical condition (for example uncontrolled infection) that may, in the opinion of the Investigator, interfere with the study objective.
• •15. Patients who had participated in other clinical trials during the previous 3 months.
• •16. Patients who have any clinical condition, according to the investigator, who does not allow safe fulfilment of clinical trial protocol.