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Feasibility and Preliminary Efficacy of the Unified Protocol in a Blended Format for Emotional Disorders in Primary Care: A Pilot Randomized Controlled Trial
The goal of this clinical trial is to learn if a "blended" therapy format (combining face-to-face therapy sessions with a smartphone app) works to treat emotional disorders, such as depression and anxiety, in adults. It will also see if this blended format is feasible and acceptable for patients in primary care settings. The main questions it aims to answer are: Does the blended therapy format reduce symptoms of depression and anxiety? Is the blended format as effective as standard face-to-face therapy? Do participants find the smartphone app easy and helpful to use? Researchers will compare the blended therapy group to a standard face-to-face therapy group and a wait-list control group to see if the blended approach works well. Participants will: Attend therapy sessions based on the Unified Protocol (a type of cognitive-behavioral therapy) for about 10 weeks. Use a smartphone app to complete exercises and track their emotions (if assigned to the blended group). Answer questionnaires about their symptoms and quality of life at the beginning, at the end of treatment, and 3 months later.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Aydin Adnan Menderes University
Aydın, Manisa, Turkey (Türkiye)
Start Date
February 1, 2026
Primary Completion Date
August 1, 2026
Completion Date
October 1, 2026
Last Updated
February 25, 2026
45
ESTIMATED participants
Unified Protocol
BEHAVIORAL
Lead Sponsor
Aydin Adnan Menderes University
NCT07360600
NCT06793397
Data Source & Attribution
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