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Comparison of Flow-Controlled and Volume-Controlled Ventilation During Bariatric Surgery: A Prospective Randomized Trial
This prospective trial aims to compare the effects of flow-controlled ventilation (FCV) and volume-controlled ventilation (VCV) on intraoperative airway pressures and oxygenation in bariatric surgery under general anesthesia. Obesity is associated with altered respiratory mechanics, reduced functional residual capacity, and increased airway pressures, making the selection of an optimal ventilation strategy particularly important in this patient population. Adult patients aged 18-65 years with a body mass index ≥30 kg/m² and American Society of Anesthesiologists (ASA) physical status II-III will be allocated to receive either FCV or VCV as part of routine intraoperative mechanical ventilation. Ventilatory parameters, including peak and plateau airway pressures, pulmonary compliance, will be recorded at predefined intraoperative time points. The primary endpoint of the study is the PaO₂ value measured at the 20th minute under an FiO₂ of 0.8-1.0. By providing comparative data on respiratory mechanics and oxygenation, this study aims to contribute to the identification of lung-protective ventilation strategies and to optimize intraoperative ventilatory management in bariatric surgery.
Age
18 - 65 years
Sex
ALL
Healthy Volunteers
No
Ankara Etlik City Hospital
Ankara, Turkey (Türkiye)
Start Date
February 24, 2026
Primary Completion Date
February 5, 2027
Completion Date
February 18, 2027
Last Updated
February 25, 2026
40
ESTIMATED participants
FCV Group
PROCEDURE
VCV Group
PROCEDURE
Lead Sponsor
Ankara Etlik City Hospital
NCT01143454
NCT07472881
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