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Retrospective Study Evaluating the Effectiveness and Safety of Immunotherapy With Clustoid®/Clustek®/Alxoid® for the Treatment of Dermatophagoides/Blomia Tropicalis Allergy in Real-Life Conditions
House dust mites are the main source of allergies in indoor environments. They are predominant in coastal areas, with the Canary Islands being the autonomous community with the highest percentage of patients with rhinoconjunctivitis due to sensitisation to these mites (94.7%). Immunotherapy is indicated for the treatment of allergic rhinoconjunctivitis and is capable of altering the natural course of allergic diseases. The aim of the study was to evaluate the efficacy and safety of Clustoid® Max Forte in the treatment of patients with respiratory allergy to Dermatophagoides/Blomia tropicalis.
Retrospective observational study of the effectiveness and safety of Clustoid® Max Forte for Dermatophagoides (D. pteronyssinus, D. farinae)/ Blomia tropicalis at concentrations of 30,000/30,000 Titer Units per milliliter (TU/mL) or 30,000/10,000 TU/mL in patients with allergic rhinitis/rhinoconjunctivitis with/without asthma, treated for a minimum of 1 year. To assess effectiveness, the combined symptom and medication scores (PSPM) for rhinitis/rhinoconjunctivitis and asthma prior to treatment (T=0) and annually up to 5 years post-initiation (T=5) were studied and compared. To assess safety, adverse reactions were collected and evaluated.
Age
5 - 65 years
Sex
ALL
Healthy Volunteers
No
Clínica Doctor García Robaina
Santa Cruz de Tenerife, Canary Islands, Spain
Nuestra Señora de Candelaria
Santa Cruz de Tenerife, Canary Islands, Spain
Start Date
March 31, 2025
Primary Completion Date
August 31, 2025
Completion Date
December 31, 2025
Last Updated
February 23, 2026
140
ACTUAL participants
Clustoid® Max Forte
BIOLOGICAL
Lead Sponsor
Inmunotek S.L.
NCT06920771
NCT04874714
Data Source & Attribution
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