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The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults | Clinical Trials | Clareo Health

NOT_YET_RECRUITINGNA

The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults

NCT07389226•University of Chicago

View on ClinicalTrials.gov

Summary

This is a single-center prospective cohort study to evaluate the effect of short-term daily apple cider vinegar (ACV) supplementation on urine chemistry.

Detailed Description

The primary objective of this study is to determine whether a two-week course of daily ACV supplementation significantly changes an individual's urine chemistry. The investigators will study this in healthy individuals and individuals with kidney stones.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

Inclusion Criteria

•Controls: Adults above the age of 18.
•Kidney stone patients: Adults above the age of 18.
•History of majority (\>50%) calcium oxalate kidney stones

Exclusion Criteria

•Anyone with a history of calcium phosphate stones (\>50% calcium phosphate), uric acid stones, struvite stones, recent urinary tract instrumentation (\<30 days), or recurrent urinary tract infections.
•Any individual who has had ACV outside of normal consumption in the prior month will be excluded.
•Any individual who has a history of a negative reaction (increased acid reflux, allergy) to ACV will also be excluded.
•Any individual with chronic kidney disease, underlying acid base disorder will also be excluded.

Locations (1)

The University of Chicago

Chicago, Illinois, United States

Key Dates

Start Date

March 1, 2026

Primary Completion Date

January 1, 2028

Completion Date

February 1, 2028

Last Updated

February 5, 2026

Enrollment

ESTIMATED participants

Conditions

Kidney StonesUrine Specimen Collection

Interventions

Apple Cider Vinegar

DIETARY_SUPPLEMENT

Contacts

Luke Reynolds

CONTACT

7137926105 lukereynolds@bsd.uchicago.edu

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: February 5, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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The Effect of Apple Cider Vinegar Supplementation on 24-hour Urine Chemistry in Adults

Inclusion Criteria

Exclusion Criteria

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