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Effects of Lower Body Plyometric Training on Serum CPK and Creatinine Levels in Collegiate Female Volleyball Players: An Experimental Study
Eight-week interventional study to evaluate whether lower-body plyometric training alters serum creatine phosphokinase (CPK) and creatinine levels in female collegiate volleyball players. Sixty participants were randomized to experimental (plyometrics twice weekly) or control (routine volleyball) groups. Blood sampling occurred at baseline; days 2, 4, and 6; and weeks 1, 2, 4, 6, and 8.
Intervention adapted from James \& Robert (2015). Experimental group completed progressive lower-body plyometrics twice weekly (Monday/Wednesday) over eight weeks with warm-up and cool-down. Exercises included squat jump; jump to box (30 cm); tuck jump; split squat jump; lateral hurdle jump (50 cm); zigzag jump; single-leg tuck jump; and depth jump (80 cm). Control group continued routine volleyball activities and did not perform low/medium/high-intensity plyometrics. Primary biomarker (serum CPK) assessed via CK-NAC optimized IFCC method; serum creatinine by modified Jaffe's method. Two-way ANOVA with Bonferroni post hoc used. Findings: CPK increased from day 2, peaked day 4, stabilized to week 2, then declined toward baseline by week 8; creatinine remained stable.
Age
18 - 25 years
Sex
FEMALE
Healthy Volunteers
Yes
Dr. Mariam Salem
Jeddah, Saudi Arabia
Start Date
January 12, 2022
Primary Completion Date
May 15, 2022
Completion Date
October 25, 2022
Last Updated
January 20, 2026
60
ACTUAL participants
plyometric program
OTHER
Lead Sponsor
Cairo University
Data Source & Attribution
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Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT06937190