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RECRUITINGNANCT07347028

Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Knee Osteoarthritis(OA)

Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Knee osteoarthritis is a common typ...

Lead sponsor: Beijing Tiantan Hospital•1 locations•View source on ClinicalTrials.gov

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Contacts

Fang Luo

CONTACT

+86 13611326978 13611326978@163.com

Sponsors

Lead Sponsor

Beijing Tiantan Hospital

Age

45 - No limit years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•Diagnosis of knee osteoarthritis with radiographic evidence of osteoarthritis (Kellgren-Lawrence grade 1-4) confirmed by at least two orthopedic surgeons, pain specialists, or general practitioners, with physical examination confirming at least one myofascial trigger point;
•Disease duration exceeding 3 months;
•Age ≥ 45 years;
•Numerical Rating Scale (NRS) score ≥ 3 points despite prior conservative pharmacological treatment;
•Signed informed consent form.

Exclusion Criteria

•History of allergy to trial medications such as corticosteroids;
•Alcohol abuse; long-term use of opioids (exceeding 2 weeks or more than 3 days per week for over 1 month); suspected use of sedative or analgesic medications; patients on long-term steroid therapy;
•Severe neurological disorders, significant hepatic or renal dysfunction, heart failure, coagulation abnormalities, gastric ulcer, diabetes, inflammatory rheumatic diseases, etc.;
•Intra-articular injection within the past 6 months or planned joint replacement surgery;
•Inability to use pain assessment scales;
•Presence of local or systemic infection;
•Pregnant or lactating patients.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: January 16, 2026Terms

Trial snapshot

StatusRECRUITING

PhaseNA

Enrollment1,036

Start dateDec 2025

Last updatedJan 16, 2026

Condition

Myofascial Trigger Points Migraine Cervicogenic Headache Chronic Musculoskeletal Pain

Locations shown

Beijing Tiantan Hospital

Beijing, Beijing Municipality

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: January 16, 2026Data synced to Clareo: May 10, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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