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RECRUITINGNANCT06735833

MMA Embolization for Refractory Chronic Migraine

This is a prospective, multi-center, feasibility study to investigate safety and effectiveness of TRUFILL n-BCA liquid embolic system in bilateral middle meningeal artery (MMA) embolization for the tr...

Lead sponsor: Cerenovus, Part of DePuy Synthes Products, Inc.•9 U.S. locations•View source on ClinicalTrials.gov

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Contacts

Study Contact

CONTACT

RA-MIGRAINECNV202302@ITS.JNJ.com

Sponsors

Lead Sponsor

Cerenovus, Part of DePuy Synthes Products, Inc.

Age

18 - 65 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•1. Patient is between 18 and 65 years of age (inclusive) at the time of consent.
•2. Age of onset of Chronic Migraine ≤ 64 years.
•3. Age of onset of migraine diagnosis \< 50 years.
•4. Patient has a current diagnosis of refractory migraine.
•5. Patient has a current diagnosis of Chronic migraine.

Exclusion Criteria

•1\. Patients with a history for the last 2 years of other types of headache. 2. Patients with diagnosis of hemiplegic migraine or migrainous infarct. 5. Patients with current regular use of Opioids, Cannabis, Medical Marijuana, etc.
•6\. Women who are pregnant, lactating, or who are of childbearing age. 7. Current involvement in an investigational (drug, device, etc.) clinical trial that may confound study endpoints. Patients in observational, natural history, and/or epidemiological studies not involving intervention are eligible. Sponsor approval is required.

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: April 17, 2026Terms

Trial snapshot

StatusRECRUITING

PhaseNA

Enrollment70

Start dateApr 2025

Last updatedApr 17, 2026

Condition

Locations shown

Barrow Neurological Institute at St. Joseph's Hospital

Phoenix, Arizona

John Muir Physician Network Clin. Research Center

Walnut Creek, California

Hartford Hospital

Hartford, Connecticut

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: April 17, 2026Data synced to Clareo: May 25, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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