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The Effect of Ultrasound Guided External Oblique and Rectus Abdominis Plane Block (EXORA) on Neuroendocrine Stress Response in Adults Undergoing Umbilical Hernia Surgery: A Prospective Randomized Controlled Trial
This study aims to evaluate the efficacy of ultrasound-guided external oblique and rectus abdominis plane block on the neuroendocrine stress response and postoperative analgesia in adults undergoing umbilical hernia repair.
Umbilical hernias of the abdomen are defined as a non-inguinal, non-hiatal defect in the fascia of the abdominal wall. Surgical stress response refers to the physiologic response to surgery and the hormonal and metabolic changes that follow it. Fascial plane blocks are gaining attention for perioperative analgesia due to their efficacy and safety profiles. The external oblique and rectus abdominis plane (EXORA) block is an emerging technique that provides a sensory block to the anterolateral abdominal wall, potentially filling gaps left by other commonly used blocks, such as the quadratus lumborum (QLB) or erector spinae plane (ESP) blocks.
Age
21 - 65 years
Sex
ALL
Healthy Volunteers
No
Tanta University
Tanta, Egypt
Start Date
August 1, 2025
Primary Completion Date
September 1, 2026
Completion Date
September 1, 2026
Last Updated
January 8, 2026
100
ESTIMATED participants
General anesthesia
OTHER
External oblique and rectus abdominis plane (EXORA) block
OTHER
Lead Sponsor
Tanta University
NCT07485530
NCT07286591
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