Left Ventricular Myocardial Work for Predicting Response to CRT

Exclusion Criteria

• •Participants will be excluded if they meet any of the following criteria:
• •1. Clinically significant cardiac valve regurgitation (≥ mild severity)
• •2. Respiratory diseases: acute or chronic respiratory disorders
• •3. Endocrine diseases: thyroid disease, diabetes mellitus, hyperaldosteronism, pheochromocytoma, etc.
• •4. Abnormal liver function (alanine transaminase \> 2× upper limit of normal), abnormal renal function (elevated creatinine beyond normal range), or dyslipidemia (elevated triglycerides, total cholesterol, low-density lipoprotein, or high-density lipoprotein)
• •5. Other systemic diseases: anemia, malignancy, connective tissue disease, large artery/peripheral vascular diseases (aortic dilation, aortic dissection, coarctation of the aorta, Takayasu arteritis, atherosclerosis), etc.
• •6. Pregnant or lactating women
• •7. Professional athletes
• •8. Poor-quality ultrasound images that cannot support parameter measurement and analysis
• •Heart failure patients with LBBB who are scheduled for CRT treatment Group
• •1. Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis;
• •2. Having a history of blood diseases and severe systemic diseases such as infections;
• •3. Those who cannot cooperate with the examinations.
• •Patients with LBBB who have preserved LVEF Group
• •1. Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis;
• •2. Having a history of blood diseases and severe systemic diseases such as infections;
• •3. Those who cannot cooperate with the examinations.
• •Patients with reduced LVEF but without LBBB Group
• •1. Suffering from connective tissue diseases such as systemic lupus erythematosus, polymyositis, and rheumatoid arthritis;
• •2. Having a history of blood diseases and severe systemic diseases such as infections;
• •3. Those who cannot cooperate with the examinations.