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Topical Use of 2% Tofacitinib for Nail Psoriasis: an Exploratory Clinical Study | Clinical Trials | Clareo Health

NOT_YET_RECRUITINGPHASE2

Topical Use of 2% Tofacitinib for Nail Psoriasis: an Exploratory Clinical Study

NCT07313072•Hexsel Dermatology Clinic

Summary

To evaluate the efficacy and safety of topical 2% tofacitinib nail lacquer in nail psoriasis, using the NAPSI and DLQI scales before and after 26 weeks of treatment.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Inclusion Criteria

•Presence of nail psoriasis in at least one fingernail or toenail;
•Patients not using systemic medication, or without adequate response to systemic medication after at least 6 months of use;
•Ability to read, understand, and sign the Informed Consent Form (ICF) and the Consent Form for Images, Presentations, and Scientific Publications.

Exclusion Criteria

•History of sensitivity to any components of the study product;
•Initiation of systemic medication for nail psoriasis less than six months prior.

Key Dates

Start Date

March 1, 2026

Primary Completion Date

January 1, 2027

Completion Date

March 1, 2027

Last Updated

March 18, 2026

Enrollment

ESTIMATED participants

Conditions

Nail Psoriasis

Interventions

Topical 2% Tofacitinib

DRUG

Local Methotrexate Injections for the Treatment of Nail Psoriasis

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Nail Psoriasis

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Nail Psoriasis

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UNKNOWNNA

Nd:YAG Laser and Radiofrequency in Treatment of Fingernail Psoriasis

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: March 18, 2026Data synced to Clareo: March 29, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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