An Exploratory Research on the Efficacy and Safety of Antibacterial Absorbable Dressing in Chronic Non-healing Wounds

Exclusion Criteria

• •Severe Comorbidities : Acute myocardial infarction, heart failure, hepatitis, shock, respiratory failure, or other critical conditions requiring stabilization
• •Uncontrolled Diabetes : Fasting blood glucose \>15 mmol/L or HbA1c \>12%
• •Active Wound Hemorrhage : Bleeding precluding standard wound therapy
• •Critical Laboratory Values :
• •Serum albumin \<20 g/L Hemoglobin \<60 g/L Platelet count \<50×10⁹/L
• •Systemic Infection : Disseminated/systemic infection requiring antibiotic therapy
• •Malignancy : Advanced cancer patients，Current radiotherapy/chemotherapy，Malignant (cancer-related) ulcers
• •Untreated Burns : Full-thickness (third-degree) burns without escharotomy
• •Active Autoimmune Disease : Flare-up phase of autoimmune disorders
• •Pregnancy/Lactation : Pregnant or breastfeeding women
• •Allergy : Hypersensitivity to absorbable wound repair materials or polyhexamethylene biguanide hydrochloride
• •Non-compliance : Inability to cooperate or psychiatric disorders
• •Investigator's Discretion : Any condition deemed to compromise wound healing or study adherence