Antihypertensive Drug Selection Based on Hemodynamic Phenotypes

Exclusion Criteria

• •1. Diagnosed or highly suspected secondary hypertension;
• •2. Classified as mixed type according to hemodynamic typing;
• •3. Allergy to the intended antihypertensive medications;
• •4. Dysphagia;
• •5. Pregnant or lactating women;
• •6. Potential pregnancy plans during the trial period;
• •7. Uncorrected electrolyte disturbances;
• •8. Severe organ dysfunction;
• •9. Comorbid conditions leading to inaccurate blood pressure measurement;
• •10. Comorbid conditions or states unsuitable for noninvasive hemodynamic measurement via bioelectrical impedance;
• •11. Comorbid conditions contraindicating or requiring caution with trial medications;
• •12. Comorbid conditions affecting the absorption, distribution, metabolism, or excretion of trial drugs;
• •13. Concurrent or planned use of medications contraindicated or requiring caution with trial drugs;
• •14. Concurrent or planned use of medications interfering with trial outcomes;
• •15. Clinician's assessment deems the patient unsuitable for the trial's antihypertensive regimen;
• •16. Current participation in other clinical studies that may interfere with the conduct of this trial.