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The Effects of Morning Light Therapy on IBD Activity and Symptoms
The pilot study will focus on the effects of morning light therapy (MLT) in adult patients with ulcerative colitis (UC) who have evidence of poor sleep quality and active inflammation. The specific population is at risk for circadian rhythm sleep-wake disorders and has significant potential benefit from circadian realignment, which may lead to improved sleep quality and, ultimately, UC-related inflammatory activity. During an initial one-week lead-in period, participants will obtain baseline circadian-related labs, complete symptom-related surveys, and use a wearable device continuously to obtain baseline sleep-wake data. After the lead-in week, patients will undergo one hour of MLT while wearing wearable devices continuously and completing daily symptom surveys. At the end of four weeks of MLT, patients will obtain post-intervention circadian and inflammatory assessments in addition to completing the same symptom-related surveys.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Mount Sinai Hospital
New York, New York, United States
Start Date
March 1, 2026
Primary Completion Date
July 1, 2027
Completion Date
July 1, 2027
Last Updated
March 13, 2026
30
ESTIMATED participants
Morning Light Therapy
DEVICE
Lead Sponsor
Icahn School of Medicine at Mount Sinai
NCT06226883
NCT07245394
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