Loading clinical trials...
Loading clinical trials...
Betreat (Xaloc1) Benralizumab Study: Retrospective, Observational Study in Portuguese Hospitals to Describe Patient Characteristics, Treatment Patterns and Outcomes
Benralizumab is indicated as an add-on maintenance treatment in adult patients with severe eosinophilic asthma inadequately controlled despite high-dose inhaled corticosteroids plus long-acting β2-agonists. It has been reimbursed in Portugal as an add-on therapy since May 2019. In order of this, there is crucial need in Portugal to provide key real-word evidence on benralizumab therapy.
This is a real-world retrospective, multicentric, observational study, utilizing secondary data collection from medical records of adults patients (≥18 years) with severe asthma (maintenance treatment with high dose inhaled corticosteroids combined with long-acting agonist β2) and eosinophilic phenotype, who, at the discretion of the physician, received benralizumab accordingly to the clinical practice, in the period after the marketing authorization of benralizumab.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
Hospital Prof. Dr. Fernando Fonseca
Amadora, Portugal
HSMM
Barcelos, Portugal
CHUC - Imunoalergologia
Coimbra, Portugal
CHUC - Pneumologia
Coimbra, Portugal
CHUA
Faro, Portugal
Hospital Leiria
Leiria, Portugal
Chln - Hsm
Lisbon, Portugal
Chuln - Hsm
Lisbon, Portugal
Hospital Pedro Hispano
Matosinhos Municipality, Portugal
CHUA
Portimão, Portugal
Start Date
August 10, 2021
Primary Completion Date
November 3, 2022
Completion Date
November 3, 2022
Last Updated
October 21, 2025
74
ACTUAL participants
Lead Sponsor
AstraZeneca
NCT05691218
NCT06681545
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.
View ClinicalTrials.gov Terms and Conditions