Phase I Clinical Study of ZKY001 Eye Drops in the Treatment of Corneal Epithelial Defect

Inclusion Criteria

• •1. Men and women aged 18-70 (including threshold);
• •2. Body mass index between 19-26kg/m2 (including critical value), male weight ≥50kg, female weight ≥45kg;
• •3. Patients who have undergone Descemet's stripping endothelial keratoplasty（DSEK）, Descemet's stripping automated endothelial keratoplasty（DSAEK） or Descemet membrane endothelial keratoplasty（DMEK） and need to remove corneal epithelium during surgery (the diameter of the removed epithelium area ≥8mm);
• •4. Lacrimal secretion test (Schirmer test I) ≥10mm/5min during screening;
• •5. Limbus structure was normal under slit-lamp during screening period;
• •6. Voluntarily sign informed consent.