Innate Immune Response Monitoring Via Monocyte HLA-DR in Severe Intra-abdominal Infections at Risk of Fungal Infection

Inclusion Criteria

• •Adult patient (≥ 18 years old)
• •Patient admitted to the ICU or intermediate care unit for a severe intra-abdominal infection requiring urgent abdominal surgery
• •Presence of at least one risk factor for intra-abdominal candidiasis:
• •* Abdominal surgery within the last 7 days
• •* Supramesocolic gastrointestinal perforation
• •* Healthcare-associated intra-abdominal infection
• •* Community-acquired intra-abdominal infection in an immunocompromised patient\*
• •* Intra-abdominal infection complicated by septic shock
• •* Broad-spectrum antibiotic exposure within 72 hours prior to surgery
• •And/or a Peritonitis Score ≥ 3 out of 4
• •Patient affiliated with or benefiting from a national health insurance system
• •Patient who has received full information about the clinical study