Intranasal Administration Technique:
1. Intranasal dexmedetomidine (1 mcg/kg ideal body weight) will be diluted to a total volume of 1 ml.
2. A mucosal atomization device (MAD) will be used for administration.
3. The dose will be divided evenly, with 0.5 mL sprayed into each nostril while the patient is in a semi-recumbent position.
4. The control group will receive an equivalent volume of 0.9% saline using the same method.
Local Anesthesia A peribulbar block will be administered with a mixture of lidocaine 2% and bupivacaine 0.5% (total volume: 5 mL).
The block will be performed under aseptic conditions by an experienced anesthesiologist.
Age
65–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Patients aged ≥65 years.
2. Patients who will have stage 2 hypertension as per ACC/AHA guidelines (Systolic BP \> 140 and Diastolic BP\> 90 mmHg)
3. Elective cataract surgery under local anesthesia.
4. American Society of Anesthesiologists (ASA) physical status II or III.
You may not be if
1. Allergy or contraindication to dexmedetomidine.
2. Significant baseline bradycardia (\<50 bpm) or arrhythmias.
3. Use of sedative or anxiolytic medications.
4. History of severe hepatic, renal, or cerebrovascular diseases.
Clareo Health | Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
