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The Effect of Osteopathic Manipulative Treatment on Respiratory Function in Patients With Asthma
Asthma is a common respiratory condition that can be difficult to control despite the use of medications such as inhalers, oral steroids or even injectable medications. Osteopathic Manipulative Treatment (OMT) is a hands-on technique used to improve the chest structure and function and may help in improving breathing. Previous research showed that OMT in asthma patients, can improve the movement of the ribs and improve the "peak flow" which is the maximum rate at which a person can exhale air after taking a deep breath. However, no studies have evaluated the impact of OMT on lung inflammation. This single-site research study at University Hospitals aims to evaluate whether Osteopathic Manipulative Treatment (OMT) can reduce lung inflammation and improve breathing and lung function in adult patients with asthma. The lung function will be evaluated by Spirometry which is a test that measures how much air you can breathe in and out of your lungs, as well as how quickly and easily you can exhale air. The lung inflammation will be measured using a device that can detect how much you are breathing out Nitric Oxide which is a gas produced by inflamed cells in the lungs, this test is called: Fractional exhaled Nitric Oxide or FeNO. Approximately 100 participants will be enrolled.
Age
18 - 60 years
Sex
ALL
Healthy Volunteers
No
Allergy Immunology Associates
Mayfield Heights, Ohio, United States
Start Date
February 1, 2026
Primary Completion Date
August 1, 2026
Completion Date
August 1, 2026
Last Updated
December 3, 2025
100
ESTIMATED participants
OMT
PROCEDURE
Light touch
OTHER
Lead Sponsor
University Hospitals Cleveland Medical Center
NCT07219173
NCT02327897
NCT07486401
Data Source & Attribution
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